{"id":"W2026443722","doi":"10.1101/gad.1871610","title":"The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Richard and Susan Smith Family Foundation; American Diabetes Association","keywords":"Biology; Homeobox; Homeobox protein Nkx-2.5; Coactivator; Transcription factor; Cell biology; Homeobox A1; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001717644,0.0003241125,0.0002693929,0.0002288481,0.0002962547,0.0003631136,0.0001997806,0.0001857849,0.001863808],"category_scores_gemma":[0.0002001844,0.000181221,0.0001495073,0.0001516269,0.0003732971,0.0002660694,0.0004223454,0.0004306092,0.0004770595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002517987,"about_ca_system_score_gemma":0.0001741407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003415225,"about_ca_topic_score_gemma":0.00052822,"domain_scores_codex":[0.9998797,0.0000170091,0.000005309831,0.00003235582,0.00004212443,0.0000234917],"domain_scores_gemma":[0.9999264,0.000009891399,0.00002522158,0.000005944647,0.00001254199,0.0000198966],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002562273,0.00001017291,0.001463743,0.0001040528,0.000008351593,0.0002089755,0.00002763041,0.0001621175,0.9856969,0.0009405974,0.0002559323,0.01086531],"study_design_scores_gemma":[0.0000398383,0.0002933174,0.04891082,0.00002544288,0.00004926533,0.002865507,0.0001689772,0.001929065,0.921326,0.0008798017,0.02348869,0.00002320454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9600524,0.01601548,0.01495357,0.0007673649,0.0001314022,0.00002679077,0.0006050261,0.0002266797,0.007221288],"genre_scores_gemma":[0.9806975,0.005115613,0.004753568,0.000126938,0.0000611998,0.00001846,0.0005148145,0.0000431605,0.008668852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001863808,"threshold_uncertainty_score":0.006235063,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122001464368739,"score_gpt":0.2482386393594535,"score_spread":0.2360384929225796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}