{"id":"W2026443722","doi":"10.1101/gad.1871610","title":"The homeobox protein Prox1 is a negative modulator of ERRα/PGC-1α bioenergetic functions","year":2010,"lang":"en","type":"article","venue":"Genes & Development","topic":"Adipose Tissue and Metabolism","field":"Medicine","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Richard and Susan Smith Family Foundation; American Diabetes Association","keywords":"Biology; Homeobox; Homeobox protein Nkx-2.5; Coactivator; Transcription factor; Cell biology; Homeobox A1; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002234834,0.000178817,0.0002618984,0.00008491368,0.0002372113,0.00001399551,0.0001302361,0.00009335644,0.000201251],"category_scores_gemma":[0.0000696338,0.0001149342,0.00007106522,0.0002502601,0.0001371106,0.0000439662,0.00007551746,0.0001878042,0.0001470095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002723776,"about_ca_system_score_gemma":0.0005158599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004210022,"about_ca_topic_score_gemma":0.00008150631,"domain_scores_codex":[0.9987215,0.00002337248,0.000361576,0.0002557419,0.0003324399,0.0003053722],"domain_scores_gemma":[0.9990759,0.00002641714,0.0001253123,0.0003902965,0.0002311677,0.0001508932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001646094,0.0002894871,0.002037164,0.0001117223,0.0004847807,0.00001233371,0.00648007,0.000003116987,0.6818399,0.0014266,0.004646179,0.302504],"study_design_scores_gemma":[0.0005745904,0.00006142593,0.03615465,0.00003935923,0.0000721414,0.00001716861,0.0003007281,0.0000190331,0.4896082,0.0002535487,0.4727592,0.0001399402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935724,0.001901839,0.000295728,0.001809141,0.0005762623,0.0009991376,0.00000581125,0.00004716423,0.0007925124],"genre_scores_gemma":[0.9598578,0.0001208203,0.01789909,0.0002394589,0.0002632607,0.0004202269,0.00001453991,0.00003377816,0.02115107],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.468113,"threshold_uncertainty_score":0.4686882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0122001464368739,"score_gpt":0.2482386393594535,"score_spread":0.2360384929225796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}