{"id":"W2026447430","doi":"10.5966/sctm.2014-0122","title":"Proceedings: International Regulatory Considerations on Development Pathways for Cell Therapies","year":2014,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Computational biology; Regulatory science; Biology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000666325,0.0001850836,0.0002739808,0.0001951113,0.0001950074,0.00001480583,0.00006782492,0.0001839638,0.0002760301],"category_scores_gemma":[0.00002283232,0.0001346168,0.0000767078,0.0001010915,0.0004454368,0.00006012032,0.000006470457,0.0001912513,0.00001728028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004860821,"about_ca_system_score_gemma":0.0001930609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001092304,"about_ca_topic_score_gemma":0.000002702424,"domain_scores_codex":[0.998201,0.00001761614,0.0004992916,0.0003225878,0.000772227,0.0001872498],"domain_scores_gemma":[0.9988682,0.000316558,0.0001295066,0.0001105656,0.0004031518,0.0001719973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007110716,0.0009103616,0.0006486074,0.000883717,0.0003434929,0.000004552262,0.01030965,0.00009550794,0.1809905,0.7169911,0.0116242,0.07648717],"study_design_scores_gemma":[0.02721782,0.002805998,0.03922107,0.001987402,0.0003589779,0.00006495265,0.001444219,0.01552468,0.1630408,0.09369358,0.6536561,0.0009843679],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3061026,0.001982394,0.09417189,0.4351137,0.007045716,0.00659285,0.0001344794,0.000732529,0.1481239],"genre_scores_gemma":[0.9880517,0.00002234399,0.007455489,0.002292208,0.0008855649,0.00007360948,0.000153343,0.00002758203,0.001038184],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6819491,"threshold_uncertainty_score":0.5489515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04163412958978083,"score_gpt":0.2697612012578463,"score_spread":0.2281270716680654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}