{"id":"W2026531251","doi":"10.1271/bbb.66.1660","title":"Functional Analyses of Tyr420 and Leu607 of <i>Alicyclobacillus acidocaldarius</i> Squalene-Hopene Cyclase. Neoachillapentaene, a Novel Triterpene with the 1,5,6-Trimethylcyclohexene Moiety…","year":2002,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Regina","keywords":"Stereochemistry; Cyclase; Triterpene; Chemistry; Squalene; Bicyclic molecule; Moiety; Steric effects; Mutant; Enzyme; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002800007,0.0003243025,0.0003547807,0.00007727919,0.0002088089,0.00002356108,0.0004602751,0.0005917329,0.00002045813],"category_scores_gemma":[0.0001547474,0.0002167238,0.00009833157,0.0004809414,0.002472796,0.00001340494,0.000306903,0.0001920594,8.091894e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001110984,"about_ca_system_score_gemma":0.00006314634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003916824,"about_ca_topic_score_gemma":0.000009267974,"domain_scores_codex":[0.998262,0.00003175463,0.0003821958,0.0007248485,0.0002565139,0.0003426961],"domain_scores_gemma":[0.9988518,0.00005447484,0.0003297759,0.0005605388,0.00009401121,0.0001093643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001897368,0.0001738656,0.001003855,0.00007479885,0.00009648441,0.000002352774,0.00001028131,0.000004388548,0.9955149,0.00003508008,0.0004808555,0.002413372],"study_design_scores_gemma":[0.0007058675,0.0003048718,0.001328439,0.00004485974,0.0000882837,0.0003155404,0.0001713847,0.00007382385,0.9939235,0.000006868985,0.002750652,0.0002859341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917293,0.005147071,0.0005464097,0.001860024,0.00003519081,0.0001470525,0.0002686277,0.00002213106,0.000244214],"genre_scores_gemma":[0.9963395,0.001943436,0.001052833,0.0002263601,0.00006153487,0.00001138254,0.00005222506,0.00001192816,0.0003008245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004610196,"threshold_uncertainty_score":0.9111119,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02414764893880383,"score_gpt":0.23432340220553,"score_spread":0.2101757532667262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}