{"id":"W2026531251","doi":"10.1271/bbb.66.1660","title":"Functional Analyses of Tyr420 and Leu607 of <i>Alicyclobacillus acidocaldarius</i> Squalene-Hopene Cyclase. Neoachillapentaene, a Novel Triterpene with the 1,5,6-Trimethylcyclohexene Moiety…","year":2002,"lang":"en","type":"article","venue":"Bioscience Biotechnology and Biochemistry","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Regina","keywords":"Stereochemistry; Cyclase; Triterpene; Chemistry; Squalene; Bicyclic molecule; Moiety; Steric effects; Mutant; Enzyme; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001135916,0.0003036434,0.000170714,0.000107591,0.0001052029,0.0002035251,0.0001139506,0.0001572765,0.0006276877],"category_scores_gemma":[0.0001766808,0.0000953417,0.0002274004,0.0001424261,0.0001562163,0.0001335605,0.0001578444,0.0002307856,0.0003557466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000286818,"about_ca_system_score_gemma":0.0001687916,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001592077,"about_ca_topic_score_gemma":0.001318441,"domain_scores_codex":[0.9999133,0.00001675634,0.000009340552,0.00001480783,0.000030349,0.00001543184],"domain_scores_gemma":[0.9998943,0.00002411768,0.00002964675,0.00001122617,0.00001676282,0.00002388002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006439494,0.0000136017,0.0001959296,0.00001588563,0.000002809127,0.00003701729,0.00001675762,0.00005920335,0.9990612,0.00004904004,0.000007490542,0.0004765862],"study_design_scores_gemma":[0.00001122719,0.0001395939,0.004121528,0.000003141489,0.00001287945,0.0002227171,0.00005129871,0.0008977992,0.9934308,0.00003470038,0.001067653,0.000006626076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980563,0.0001646163,0.0009717277,0.00003518027,0.000007445551,0.000009267639,0.0003315091,0.00001919093,0.0004047561],"genre_scores_gemma":[0.9957952,0.000184974,0.001292143,0.00003081427,0.000003284346,0.00001530276,0.001339798,0.00003039512,0.00130794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001592077,"threshold_uncertainty_score":0.003165662,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02414764893880383,"score_gpt":0.23432340220553,"score_spread":0.2101757532667262,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}