{"id":"W2026541961","doi":"10.1002/wrna.55","title":"Turnover of AU‐rich‐containing mRNAs during stress: a matter of survival","year":2010,"lang":"en","type":"review","venue":"Wiley Interdisciplinary Reviews - RNA","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôpital Saint-François d'Assise; Centre hospitalier universitaire de Québec; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Tristetraprolin; Stress granule; AU-rich element; Messenger RNA; Cell biology; P-bodies; RNA-binding protein; Cytoplasm; Untranslated region; microRNA; Biology; Rna processing; Translation (biology); RNA; Cellular stress response; Chemistry; Gene; Fight-or-flight response; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003422904,0.0002191059,0.0005777712,0.0004385066,0.0003568766,0.00130338,0.000259201,0.0006360066,0.001948396],"category_scores_gemma":[0.0004243748,0.0001104622,0.0001484377,0.0004405338,0.0004457894,0.0008804028,0.0002962736,0.0004924874,0.001343466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000495191,"about_ca_system_score_gemma":0.0002341506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001898182,"about_ca_topic_score_gemma":0.0001752001,"domain_scores_codex":[0.9997421,0.00003302822,0.00001964567,0.00008782488,0.00006962796,0.00004782489],"domain_scores_gemma":[0.9996773,0.00005306436,0.000104934,0.00002243803,0.00009053492,0.00005162117],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003522458,0.00003900891,0.004611189,0.001421898,0.00005369155,0.0005665896,0.0005264109,0.0005685257,0.8354052,0.01230185,0.003435257,0.1407182],"study_design_scores_gemma":[0.00002167749,0.001420483,0.1433767,0.0008997578,0.0002282483,0.007131137,0.002168618,0.003317204,0.5067661,0.03212677,0.3023787,0.0001645614],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.4010531,0.5480012,0.01562514,0.003267827,0.001695316,0.0000296818,0.0007784348,0.0002718691,0.02927744],"genre_scores_gemma":[0.8521041,0.1185471,0.003554769,0.0006816022,0.001025007,0.00004994883,0.0005876445,0.0001149267,0.02333493],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001948396,"threshold_uncertainty_score":0.006518006,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03498594275004988,"score_gpt":0.3584368934793787,"score_spread":0.3234509507293288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}