{"id":"W2026544533","doi":"10.1071/rdv27n1ab331","title":"331 ABNORMAL DNA METHYLATION PATTERNS AND ALLELE-SPECIFIC EXPRESSION OF IMPRINTED GENES IN BOVINE-INDUCED PLURIPOTENT STEM CELLS","year":2014,"lang":"en","type":"article","venue":"Reproduction Fertility and Development","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Cegep de Saint Hyacinthe","funders":"","keywords":"Biology; Reprogramming; Genomic imprinting; DNA methylation; SOX2; Genetics; Homeobox protein NANOG; XIST; Epigenetics; Molecular biology; Differentially methylated regions; Methylation; Gene; Induced pluripotent stem cell; Gene expression; Embryonic stem cell; X-inactivation; X chromosome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001152132,0.0001784737,0.0001396399,0.0003420273,0.00009838654,0.0001846343,0.0001044898,0.0001494883,0.0005813792],"category_scores_gemma":[0.0001375338,0.0001277599,0.000139728,0.0001838445,0.0001391493,0.00009456049,0.0001416332,0.0001788401,0.0002202556],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001696673,"about_ca_system_score_gemma":0.00008815106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002171888,"about_ca_topic_score_gemma":0.002221143,"domain_scores_codex":[0.9998912,0.00001321694,0.00001373755,0.00002770323,0.00003524814,0.00001889466],"domain_scores_gemma":[0.9999034,0.00001782492,0.00004075273,0.000009475614,0.00001305779,0.00001541601],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002961439,0.000002700802,0.001928229,0.00001707678,0.000003339247,0.00007629305,0.00003426201,0.0000291904,0.9968339,0.00002301478,0.000006242861,0.001016244],"study_design_scores_gemma":[0.000007541233,0.0002584666,0.1492499,0.00001630608,0.00005543325,0.001914238,0.0001398663,0.001018678,0.8434446,0.0001072549,0.003776223,0.00001148692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912022,0.001743057,0.005141568,0.00002708855,0.000008595298,0.00001190574,0.0005276357,0.00004687857,0.001291055],"genre_scores_gemma":[0.9954631,0.0006884407,0.001774984,0.00002534489,0.000003321157,0.00001086307,0.0009912837,0.00001428633,0.001028379],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002171888,"threshold_uncertainty_score":0.004318476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02528269986142197,"score_gpt":0.2481968287140952,"score_spread":0.2229141288526732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}