{"id":"W2026560661","doi":"10.1016/j.bbrc.2011.08.043","title":"Crystal structure of the Cys2His2-type zinc finger domain of human DPF2","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Structural Genomics Consortium; Canadian Institutes of Health Research; Argonne National Laboratory; National Natural Science Foundation of China","keywords":"Zinc finger; RING finger domain; LIM domain; Zinc; Transcription factor; Domain (mathematical analysis); Crystallography; DNA; Zinc finger nuclease; Chemistry; Protein structure; Stereochemistry; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676502,0.0002638887,0.0002858352,0.0001127727,0.0002797092,0.0003260448,0.0002875817,0.0002699737,0.001612],"category_scores_gemma":[0.0001791099,0.0001300155,0.0001053213,0.0002080378,0.0001404355,0.0001718506,0.0001236535,0.0005597486,0.0002839692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000610714,"about_ca_system_score_gemma":0.0003508299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002995506,"about_ca_topic_score_gemma":0.003890893,"domain_scores_codex":[0.9999535,0.000004780972,0.000002645591,0.00001088739,0.00001875477,0.000009481584],"domain_scores_gemma":[0.9999497,0.00001153567,0.00000744336,0.000002890871,0.00001001468,0.00001851298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002423426,0.0003979345,0.01320556,0.0005486319,0.0002347995,0.003765611,0.0004382012,0.009082993,0.9197628,0.005234102,0.01749422,0.02741167],"study_design_scores_gemma":[0.001604507,0.0006140025,0.1226074,0.0000898052,0.0002817634,0.007706864,0.001163616,0.081808,0.6809573,0.003034363,0.09996036,0.0001720698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879751,0.001977058,0.003170423,0.0004566655,0.0001098137,0.00002593498,0.002304649,0.0001842558,0.003796093],"genre_scores_gemma":[0.9898304,0.0005997023,0.002084737,0.0001160624,0.00001671422,0.00001729245,0.003663307,0.00001979857,0.003651975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002995506,"threshold_uncertainty_score":0.005956173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04753451765630479,"score_gpt":0.3242433353226474,"score_spread":0.2767088176663426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}