{"id":"W2026584505","doi":"10.1038/nsmb.2275","title":"Turning Dicer on its head","year":2012,"lang":"en","type":"letter","venue":"Nature Structural & Molecular Biology","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Dicer; Head (geology); Cell biology; Biology; Genetics; Computational biology; RNA interference; Gene; RNA; Paleontology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001178712,0.0006119882,0.0006182907,0.000320753,0.001661144,0.002198511,0.0007774034,0.008185606,0.006770238],"category_scores_gemma":[0.004504923,0.0004619039,0.00057031,0.000190203,0.002181222,0.002027822,0.001212642,0.01269902,0.005119028],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00170741,"about_ca_system_score_gemma":0.0006817319,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006334215,"about_ca_topic_score_gemma":0.0007819791,"domain_scores_codex":[0.9990746,0.0001350845,0.00005733832,0.0001599628,0.0004243503,0.0001487166],"domain_scores_gemma":[0.9991972,0.0003051629,0.00007743909,0.0001074698,0.0001231133,0.0001896569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007975551,0.00006802,0.00039086,0.0002767872,0.00004764233,0.004037669,0.0002122956,0.0004187008,0.05408715,0.05644004,0.7918993,0.09132395],"study_design_scores_gemma":[0.0001705935,0.0001573877,0.000396814,0.00004756822,0.00002900202,0.002785105,0.0001083497,0.0007356537,0.05342387,0.03171092,0.9103764,0.00005845933],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01080956,0.01965288,0.009157773,0.7990121,0.1029235,0.00006276895,0.0002511088,0.0009188663,0.05721142],"genre_scores_gemma":[0.1852133,0.01400757,0.008214735,0.5713101,0.04200683,0.0001952614,0.0002821364,0.0002274549,0.1785426],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.008185606,"threshold_uncertainty_score":0.02264863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0120576828538698,"score_gpt":0.3169765855503331,"score_spread":0.3049189026964633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}