{"id":"W2026597706","doi":"10.1007/s00125-008-1130-9","title":"The role of pyruvate carboxylase in insulin secretion and proliferation in rat pancreatic beta cells","year":2008,"lang":"en","type":"article","venue":"Diabetologia","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; University of Toronto; National Institutes of Health; National Center for Research Resources; American Diabetes Association","keywords":"Pyruvate carboxylase; Pyruvate dehydrogenase kinase; Pyruvate dehydrogenase complex; Pyruvate decarboxylation; PDK4; Endocrinology; Internal medicine; Insulin; Pyruvate dehydrogenase phosphatase; Biology; Beta cell; Secretion; Chemistry; Islet; Biochemistry; Enzyme; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005432894,0.0005157812,0.0003705031,0.0008129931,0.0004899657,0.0008762389,0.0004481983,0.0004521716,0.00089974],"category_scores_gemma":[0.000389542,0.0004176551,0.0004688087,0.0006436338,0.0007146114,0.001589815,0.0003988183,0.0009837563,0.0003099996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005960032,"about_ca_system_score_gemma":0.0005649216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001113232,"about_ca_topic_score_gemma":0.000782114,"domain_scores_codex":[0.9998133,0.00004871682,0.00001958117,0.00004033985,0.00003158841,0.00004660777],"domain_scores_gemma":[0.9995607,0.0001771617,0.00004041255,0.00007221328,0.00004955456,0.0001000096],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007852157,0.0000896753,0.003121788,0.0002637584,0.00004499311,0.0004648406,0.0001355381,0.0002692694,0.9761178,0.0008992687,0.00007560353,0.01066532],"study_design_scores_gemma":[0.0001598599,0.0009725034,0.02079722,0.00002419282,0.00008562773,0.0006875003,0.0002040546,0.0009910456,0.9723654,0.0006065905,0.003086024,0.0000199521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9605966,0.02935323,0.00468885,0.0004993064,0.000118327,0.00002891466,0.0006601575,0.00006557386,0.003988975],"genre_scores_gemma":[0.9867805,0.006221605,0.002824625,0.0001069005,0.00007336521,0.00003311951,0.000885462,0.00002327748,0.003051212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001113232,"threshold_uncertainty_score":0.004324317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009791727724503506,"score_gpt":0.2173148589661272,"score_spread":0.2075231312416237,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}