{"id":"W2026653305","doi":"10.1107/s0907444908013978","title":"Structure determination of an anti-HIV-1 Fab 447-52D–peptide complex from an epitaxially twinned data set","year":2008,"lang":"en","type":"article","venue":"Acta Crystallographica Section D Biological Crystallography","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health; International AIDS Vaccine Initiative; Center for AIDS Research, University of Washington; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Bill and Melinda Gates Foundation; U.S. Department of Veterans Affairs","keywords":"V3 loop; Peptide; Chemistry; Epitope; Antibody; Neutralization; Crystallography; Biology; Biochemistry; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008505216,0.0009284512,0.001597458,0.0009252376,0.000861567,0.001149409,0.002041628,0.0009346143,0.002234326],"category_scores_gemma":[0.001494696,0.0007867428,0.0006360232,0.002089122,0.0003752287,0.0004854588,0.0005217653,0.001649282,0.0005937899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001640213,"about_ca_system_score_gemma":0.001449083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007743081,"about_ca_topic_score_gemma":0.007061414,"domain_scores_codex":[0.999382,0.00008163269,0.00004856044,0.0001321859,0.0002774496,0.00007803379],"domain_scores_gemma":[0.9991421,0.0002087483,0.00009058816,0.0001212553,0.0002972303,0.0001400829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002351617,0.0005581306,0.0096,0.0009061886,0.0003544755,0.003622033,0.001362234,0.009373052,0.9457475,0.001634036,0.006886754,0.01760415],"study_design_scores_gemma":[0.001878687,0.001747038,0.1137078,0.0001621035,0.0006458916,0.005840391,0.001344959,0.1530021,0.6663345,0.001439399,0.05352639,0.0003708686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9826043,0.001490272,0.005394048,0.0002545433,0.0000746265,0.00006934322,0.007267514,0.0003856083,0.002459748],"genre_scores_gemma":[0.9039674,0.00156274,0.03107743,0.0002177403,0.00002432201,0.0001192102,0.06080411,0.0003940048,0.001832974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007743081,"threshold_uncertainty_score":0.01539606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05515089842259811,"score_gpt":0.2898390912175523,"score_spread":0.2346881927949542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}