{"id":"W2026663373","doi":"10.1016/j.pupt.2011.05.002","title":"Small animals models for drug discovery","year":2011,"lang":"en","type":"review","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Chemokine; Immune system; Asthma; Immunology; Inflammation; Innate immune system; Acquired immune system; Drug discovery; Biology; Cytokine; Translation (biology); Neuroscience; Allergy; Medicine; Bioinformatics; Genetics; Gene; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002489034,0.0008076261,0.002258036,0.0002714041,0.0001771741,0.00002512103,0.0004680513,0.0005294834,0.0001882173],"category_scores_gemma":[0.000002357281,0.0006014163,0.001384153,0.000211884,0.0002826435,0.0001329407,0.0001465308,0.0006300214,0.00008162478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001379093,"about_ca_system_score_gemma":0.0009143294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003280695,"about_ca_topic_score_gemma":8.026506e-7,"domain_scores_codex":[0.9972262,0.0002890007,0.0008232091,0.0007810036,0.0001559802,0.0007246264],"domain_scores_gemma":[0.9982839,0.000354191,0.000448391,0.0004651103,0.0001387385,0.0003096845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004920662,0.0007897689,0.0000108273,0.01239799,0.001136432,0.0001721751,0.0000540864,0.000003135215,0.00004665769,0.0001003807,0.001243462,0.983553],"study_design_scores_gemma":[0.0006439159,0.0002846698,0.000005605936,0.001491128,0.02036949,0.0002508059,0.00002823461,0.0001638379,0.0000301495,0.0003884832,0.9757901,0.0005536122],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007586569,0.993103,0.0003446796,0.0001316384,0.001033721,0.003379644,0.0004379975,0.000153696,0.001339789],"genre_scores_gemma":[0.000109854,0.9887556,0.0002934159,0.004120085,0.001313698,0.001098922,0.0002739026,0.00024161,0.003792906],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9829994,"threshold_uncertainty_score":0.9996437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1683585068553956,"score_gpt":0.3824855400709596,"score_spread":0.214127033215564,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}