{"id":"W2026691222","doi":"10.1189/jlb.0702371","title":"Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A2A receptor engagement","year":2003,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Arthritis Society","keywords":"Phospholipase D; Arachidonic acid; Adenosine; Leukotriene B4; Biology; Phospholipase A2; Lipid signaling; Endogeny; Receptor; Biochemistry; Signal transduction; Enzyme; Inflammation; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004284054,0.0001860807,0.0003566347,0.0001313813,0.00007332178,0.00001124275,0.0001192635,0.0002031534,0.0000506953],"category_scores_gemma":[0.00009665795,0.0001650708,0.000102609,0.0001056181,0.0001186431,0.00001322047,0.0000602445,0.0002531403,8.044775e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004229569,"about_ca_system_score_gemma":0.0001125168,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004282865,"about_ca_topic_score_gemma":0.000002746401,"domain_scores_codex":[0.9985566,0.0002551526,0.0006005623,0.0002311288,0.00009620714,0.0002603259],"domain_scores_gemma":[0.9991289,0.00002822166,0.0004992504,0.0001451863,0.0001094627,0.00008891772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003201227,0.0001892628,0.002782768,0.00001593087,0.00007860654,0.00001437652,0.00009171174,0.00004989989,0.9952626,0.0002752944,0.0005895941,0.0003298902],"study_design_scores_gemma":[0.001941107,0.001245432,0.0002613962,0.00002939658,0.00003472098,0.0001787533,0.0001532101,0.000002650518,0.9866003,0.0002623162,0.009134937,0.0001557106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9766995,0.02267599,0.0001960638,0.00006345774,0.0001193783,0.00010574,0.00001378127,0.000002791538,0.0001233514],"genre_scores_gemma":[0.9974003,0.001865584,0.0002923384,0.00007473437,0.000256934,0.000004646406,0.00006497772,0.00001822815,0.00002225985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0208104,"threshold_uncertainty_score":0.6731393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108267407560699,"score_gpt":0.244007718838456,"score_spread":0.2331809780823861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}