{"id":"W2026697293","doi":"10.1016/s0264-410x(03)00386-4","title":"Tularemia in BALB/c and C57BL/6 mice vaccinated with Francisella tularensis LVS and challenged intradermally, or by aerosol with virulent isolates of the pathogen: protection varies depending on pathogen virulence, route of exposure, and host genetic background","year":2003,"lang":"en","type":"article","venue":"Vaccine","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute for Biological Sciences; National Research Council Canada","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Francisella tularensis; Tularemia; Virulence; Microbiology; Pathogen; Biology; Attenuated vaccine; Virology; Immunity; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004936226,0.001289183,0.00108609,0.001382254,0.0006149728,0.0007128705,0.0006010517,0.00218187,0.002476894],"category_scores_gemma":[0.0004201226,0.0005901527,0.0007676273,0.0003122893,0.0009330195,0.001055927,0.0003723665,0.003255725,0.0006303287],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009628219,"about_ca_system_score_gemma":0.0005958717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002955392,"about_ca_topic_score_gemma":0.002283589,"domain_scores_codex":[0.9993443,0.00006302364,0.00003854101,0.0001801235,0.0001055521,0.0002684408],"domain_scores_gemma":[0.9990836,0.0001448181,0.0002177596,0.00008529476,0.0001029835,0.0003655597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005682692,0.001210346,0.0005740498,0.00009653815,0.0000332344,0.0001137163,0.0001506376,0.0001886554,0.9900542,0.0002750357,0.0002322224,0.001388469],"study_design_scores_gemma":[0.0009570996,0.02337934,0.02775886,0.00008222298,0.0002857602,0.0006703566,0.0002803686,0.003148425,0.9410934,0.0004583083,0.001789387,0.00009658391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957685,0.0009803561,0.0005561606,0.0002341075,0.0001469586,0.00005512345,0.001016869,0.0001209339,0.001120903],"genre_scores_gemma":[0.99156,0.0007107485,0.0005403721,0.0002948339,0.00006671693,0.0001157256,0.001375895,0.00004737327,0.005288239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002955392,"threshold_uncertainty_score":0.008286059,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009661712005052343,"score_gpt":0.2079704807381464,"score_spread":0.198308768733094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}