{"id":"W2026813804","doi":"10.1038/ng0505-457","title":"Universal epistasis analysis","year":2005,"lang":"en","type":"letter","venue":"Nature Genetics","topic":"Molecular Biology Techniques and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Epistasis; Biology; Multicellular organism; Phenotype; Computational biology; Genetics; Microarray analysis techniques; Genetic analysis; Evolutionary biology; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001490128,0.0005426559,0.001051818,0.001009339,0.0006427471,0.0007615903,0.001217866,0.0008916385,0.006818915],"category_scores_gemma":[0.003538327,0.00029133,0.0007239145,0.0009597648,0.001229237,0.001600828,0.001749411,0.002498629,0.001289341],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007003857,"about_ca_system_score_gemma":0.0003422512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003891009,"about_ca_topic_score_gemma":0.0007940748,"domain_scores_codex":[0.9987999,0.000426436,0.00004475881,0.0003257719,0.0002770575,0.0001260344],"domain_scores_gemma":[0.9988361,0.0004555102,0.00005672501,0.0004333919,0.0001397206,0.0000786108],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0002736917,0.00004031578,0.001364584,0.0002242774,0.000131869,0.0006258517,0.0001092127,0.002428369,0.01855355,0.6784484,0.08944313,0.2083568],"study_design_scores_gemma":[0.00006808017,0.0000539738,0.002060756,0.00004239778,0.00008433647,0.002143156,0.00005482224,0.05735018,0.01954305,0.8315275,0.08700861,0.00006306855],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"methods","genre_gemma":"commentary","genre_scores_codex":[0.02248575,0.00394454,0.9170811,0.01119058,0.002967804,0.00008062211,0.0005677914,0.002534789,0.03914705],"genre_scores_gemma":[0.6795709,0.002436371,0.2757288,0.007740725,0.001848376,0.0001905667,0.0008522015,0.0009779441,0.03065414],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.006818915,"threshold_uncertainty_score":0.02281153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004998081804888688,"score_gpt":0.2606643175325047,"score_spread":0.255666235727616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}