{"id":"W2026918197","doi":"10.1002/dvdy.21685","title":"Integrin‐linked kinase regulates E‐cadherin expression through PARP‐1","year":2008,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":76,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation","keywords":"Biology; Gene silencing; Integrin-linked kinase; Transcription factor; Snail; Cell biology; Molecular biology; Poly ADP ribose polymerase; Cancer research; Kinase; Protein kinase A; Polymerase; Genetics; Gene; Cyclin-dependent kinase 2","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074533,0.0002233855,0.000318487,0.00006028299,0.0001543672,0.00001269585,0.0001037876,0.000111059,0.0003720105],"category_scores_gemma":[0.00003127422,0.0001892546,0.0001048972,0.0002242625,0.0001207988,0.0001363572,0.0001108351,0.0002178752,0.0001126201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004793789,"about_ca_system_score_gemma":0.0002116512,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001374203,"about_ca_topic_score_gemma":0.0000747714,"domain_scores_codex":[0.9987215,0.00001843065,0.0003210205,0.0003304155,0.0002939343,0.0003147303],"domain_scores_gemma":[0.9994764,0.0000225727,0.00007597253,0.0002114508,0.0000654625,0.0001480803],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003342461,0.002644829,0.2159959,0.001081057,0.0008335852,0.004165691,0.01918552,0.0001213811,0.439844,0.00359592,0.0563678,0.2528219],"study_design_scores_gemma":[0.01060271,0.0005816047,0.2748435,0.001293158,0.0002096388,0.00372288,0.004500984,0.002690449,0.3973285,0.000905722,0.3013458,0.001975097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9840879,0.0003093377,0.001311359,0.0002648253,0.0003503456,0.0003012627,0.00002859169,0.0001198593,0.0132265],"genre_scores_gemma":[0.9280421,0.0008407912,0.06333417,0.0005487819,0.00008595509,0.00003331948,0.0003362673,0.00004393108,0.006734703],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2508467,"threshold_uncertainty_score":0.7717578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02883464232019193,"score_gpt":0.2603373639346463,"score_spread":0.2315027216144544,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}