{"id":"W2026941773","doi":"10.1097/00005344-200402000-00018","title":"Protein Kinase C Masks Nitric Oxide Synthase Activity in Vascular Smooth Muscle under Basal Conditions","year":2004,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Calphostin C; Nitric oxide synthase; Calphostin; Protein kinase C; Nitric oxide; Phenylephrine; Vascular smooth muscle; Endocrinology; Internal medicine; Omega-N-Methylarginine; Contraction (grammar); Nitroarginine; Protein kinase A; Endothelium-derived relaxing factor; Arginine; Chemistry; Biology; Biochemistry; Kinase; Medicine; Smooth muscle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002740326,0.0004112659,0.0003187994,0.0001786419,0.0002263895,0.0003591812,0.000317573,0.0003184191,0.002430462],"category_scores_gemma":[0.0002624136,0.0001596817,0.0001776253,0.0002415147,0.0003697651,0.0003266568,0.0002100767,0.0008682891,0.0006719899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004324472,"about_ca_system_score_gemma":0.0006339771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00114275,"about_ca_topic_score_gemma":0.001543011,"domain_scores_codex":[0.9996992,0.00004991614,0.00002028356,0.00008983337,0.00006844233,0.00007233544],"domain_scores_gemma":[0.9998622,0.00002548067,0.00002968915,0.00002202121,0.00002189333,0.00003864079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002039876,0.00003120356,0.0000602029,0.00006048679,0.000004052104,0.0000216008,0.000008375896,0.00002179482,0.9985007,0.0001591898,0.00005626896,0.0008721086],"study_design_scores_gemma":[0.0000635375,0.0003249169,0.003507896,0.00001509591,0.00001952366,0.0002219619,0.00001656448,0.00121783,0.9892411,0.0001369129,0.005227714,0.000006878745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9786013,0.007960081,0.006843031,0.0004682564,0.0003403401,0.00007394255,0.000847425,0.0001537289,0.004711783],"genre_scores_gemma":[0.9825628,0.003546477,0.006141233,0.000164478,0.0001048701,0.0001173659,0.001904848,0.00003172881,0.005426309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002430462,"threshold_uncertainty_score":0.008130729,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01645535888208395,"score_gpt":0.2896917305149698,"score_spread":0.2732363716328858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}