{"id":"W2026959738","doi":"10.1016/j.bpj.2008.12.2723","title":"Photoreceptor ABC Transporter ABCA4: Its Role in the Visual Cycle and Retinal Degenerative Diseases","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"ABCA4; Stargardt disease; Retinitis pigmentosa; Retinal degeneration; Visual phototransduction; Dystrophy; Retinaldehyde; Biology; Cell biology; Rhodopsin; Retinal; Retinal pigment epithelium; Lipofuscin; Opsin; ATP-binding cassette transporter; Biophysics; Biochemistry; Genetics; Transporter; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000224186,0.0002445089,0.000470335,0.0003835771,0.0003423006,0.0008683313,0.0003091826,0.000761426,0.001950835],"category_scores_gemma":[0.0004689841,0.0001665179,0.000152275,0.0003321749,0.0005528132,0.0007241609,0.0002906171,0.0005771487,0.0003670841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007190703,"about_ca_system_score_gemma":0.0003863415,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001238574,"about_ca_topic_score_gemma":0.0006861038,"domain_scores_codex":[0.9999223,0.0000245272,0.000006689408,0.00001249312,0.00001824724,0.00001583954],"domain_scores_gemma":[0.9999003,0.00002065899,0.00002106316,0.00001003424,0.00002617181,0.00002166168],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003841726,0.0001469003,0.01000437,0.0004749935,0.0000879264,0.002719208,0.0001176933,0.001511382,0.9029768,0.01440712,0.003908354,0.05980356],"study_design_scores_gemma":[0.0005916536,0.001109567,0.08443069,0.0001326302,0.0004097605,0.01755485,0.0008044786,0.03220366,0.7287637,0.04398805,0.08983284,0.0001781514],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9130096,0.06566045,0.005893607,0.008470791,0.0003248205,0.00002171976,0.0002992715,0.0001537144,0.006166071],"genre_scores_gemma":[0.9838248,0.00999272,0.001378818,0.0002873892,0.0001216783,0.00001143891,0.000124177,0.00001570291,0.00424332],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001950835,"threshold_uncertainty_score":0.006526172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004493041268684829,"score_gpt":0.2399223811951082,"score_spread":0.2354293399264234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}