{"id":"W2027001273","doi":"10.1039/c3cs60439j","title":"Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine","year":2014,"lang":"en","type":"review","venue":"Chemical Society Reviews","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1099,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Rolling circle replication; Nanobiotechnology; Nanotechnology; DNA; DNA nanotechnology; DNA origami; RNA; Nucleic acid; Computational biology; Loop-mediated isothermal amplification; Biology; Polymerase; Materials science; Nanostructure; Genetics; Nanoparticle","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000946125,0.001176683,0.001135548,0.001724847,0.000571636,0.001596757,0.001301418,0.001386977,0.002241048],"category_scores_gemma":[0.0006035531,0.0006902622,0.0006243786,0.001693203,0.001220728,0.001840254,0.001242128,0.002390764,0.002752255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007417045,"about_ca_system_score_gemma":0.0007291819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000324254,"about_ca_topic_score_gemma":0.000350537,"domain_scores_codex":[0.9986278,0.0001884037,0.00006548147,0.0002829489,0.0007303131,0.0001050464],"domain_scores_gemma":[0.9997414,0.00007924171,0.00004488833,0.00003383809,0.0000616317,0.00003903876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001632441,0.000106938,0.0003417636,0.003353833,0.00007907071,0.0006106985,0.0002655529,0.001224342,0.5631734,0.03498452,0.02139191,0.3743046],"study_design_scores_gemma":[0.00002810852,0.0002948413,0.00034124,0.0002349866,0.0000522116,0.001531183,0.00004729348,0.002951575,0.3471475,0.005332037,0.6419303,0.0001086877],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01646586,0.5594378,0.375463,0.003007008,0.002694075,0.0003469455,0.0009224743,0.004715559,0.0369473],"genre_scores_gemma":[0.166685,0.4506845,0.3356212,0.002570166,0.00212449,0.00104824,0.00192742,0.0005697072,0.03876931],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002241048,"threshold_uncertainty_score":0.007497072,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04625316749256814,"score_gpt":0.3793305830189751,"score_spread":0.333077415526407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}