{"id":"W2027091658","doi":"10.1021/bi060112o","title":"Ligand Interactions in the Distal Heme Pocket of <i>Mycobacterium tuberculosis</i> Truncated Hemoglobin N:  Roles of TyrB10 and GlnE11 Residues","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Heme; Chemistry; Hydrogen bond; Ligand (biochemistry); Residue (chemistry); Stereochemistry; Crystallography; Resonance Raman spectroscopy; Hemeprotein; Protein structure; Molecule; Raman spectroscopy; Biochemistry; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001207618,0.0001730044,0.0001541592,0.00003088529,0.0001078973,0.000140186,0.0002022052,0.0001657793,0.0003800758],"category_scores_gemma":[0.00011135,0.00007968692,0.00007560028,0.00003526671,0.0001915876,0.0001376328,0.0001160205,0.0002430451,0.0001256139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002309377,"about_ca_system_score_gemma":0.0001201596,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154237,"about_ca_topic_score_gemma":0.001104755,"domain_scores_codex":[0.9999352,0.00001483624,0.000003132523,0.00001730601,0.00001461768,0.00001489651],"domain_scores_gemma":[0.9999468,0.00001340761,0.00001615594,0.000003258838,0.000006091192,0.00001416988],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002343469,0.00002406073,0.00111085,0.000031192,0.000004171159,0.0001159766,0.00003518156,0.0003953893,0.9964893,0.0001126266,0.00004688717,0.001399982],"study_design_scores_gemma":[0.00005263523,0.0003911767,0.01978192,0.00001347565,0.00001990536,0.0006222157,0.0001589563,0.01107774,0.9659357,0.0002235243,0.001701012,0.00002171241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990199,0.0001885811,0.0006126511,0.0000220902,0.000002269004,0.000001025289,0.00001105246,0.000008391319,0.0001340523],"genre_scores_gemma":[0.9991577,0.00007943386,0.0004683261,0.00002707208,0.000001296475,0.000001132331,0.00003293759,0.000003866336,0.0002283241],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001154237,"threshold_uncertainty_score":0.002295077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004517492364929322,"score_gpt":0.2210112754049889,"score_spread":0.2164937830400595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}