{"id":"W2027091658","doi":"10.1021/bi060112o","title":"Ligand Interactions in the Distal Heme Pocket of <i>Mycobacterium tuberculosis</i> Truncated Hemoglobin N:  Roles of TyrB10 and GlnE11 Residues","year":2006,"lang":"en","type":"article","venue":"Biochemistry","topic":"Hemoglobin structure and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Heme; Chemistry; Hydrogen bond; Ligand (biochemistry); Residue (chemistry); Stereochemistry; Crystallography; Resonance Raman spectroscopy; Hemeprotein; Protein structure; Molecule; Raman spectroscopy; Biochemistry; Receptor; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001160278,0.0001510706,0.0001688419,0.00002767621,0.00003606317,0.0000148482,0.0001343016,0.0001279237,0.000009824675],"category_scores_gemma":[0.00004343676,0.0001198147,0.0000720922,0.0001295951,0.0001414741,0.000005906608,0.00006034415,0.00009603554,4.084205e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001129387,"about_ca_system_score_gemma":0.00004252586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001288454,"about_ca_topic_score_gemma":0.0001227752,"domain_scores_codex":[0.9991391,0.00003408328,0.0003107932,0.000248917,0.000116677,0.0001504117],"domain_scores_gemma":[0.9994543,0.00002020008,0.0001252173,0.0003049959,0.00006780489,0.00002752835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000118243,0.00007935847,0.01463975,0.00008209472,0.00002126773,0.000001524009,0.00004552079,0.000002781296,0.9820434,0.00001925203,0.00265888,0.0002879115],"study_design_scores_gemma":[0.0003816867,0.0000602695,0.01625679,0.00003272549,0.00002657735,0.00005005626,0.0003103178,0.000005979768,0.9794769,0.00008063835,0.003196387,0.0001216916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996613,0.001130417,0.00002922567,0.0001504856,0.00006375728,0.00009584317,0.0001118782,0.000006103512,0.001799333],"genre_scores_gemma":[0.998968,0.00007625409,0.0001073856,0.00007613948,0.0001823919,0.00001003201,0.0003817966,0.00001094698,0.0001870289],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00256654,"threshold_uncertainty_score":0.4885902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004517492364929322,"score_gpt":0.2210112754049889,"score_spread":0.2164937830400595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}