{"id":"W2027114238","doi":"10.1002/jlcr.862","title":"Synthesis of <sup>14</sup>C‐labelled EM‐800 (SCH 57050) and EM‐652·HCl (SCH 57068·HCl, acolbifene), pure selective estrogen receptor modulators","year":2004,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Diastereomer; Racemization; Yield (engineering); Radiosynthesis; Amine gas treating; Racemic mixture; Moiety; Hydrochloride; Resolution (logic); Nuclear chemistry; Salt (chemistry); Resorcinol; Enantiomeric excess; Stereochemistry; Medicinal chemistry; Enantiomer; Organic chemistry; Enantioselective synthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002029273,0.0005662725,0.0003610766,0.0002043847,0.0001805613,0.0001914065,0.0004659647,0.0003873706,0.00354281],"category_scores_gemma":[0.0001917199,0.000264671,0.0002302164,0.000243014,0.0001585248,0.0002484178,0.0002101148,0.0004872395,0.002488753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003571136,"about_ca_system_score_gemma":0.0005569638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000711572,"about_ca_topic_score_gemma":0.001324332,"domain_scores_codex":[0.9998784,0.00002234496,0.00001010491,0.00002670517,0.0000290348,0.00003331365],"domain_scores_gemma":[0.9998999,0.000013713,0.00001940319,0.00001471515,0.00002713162,0.00002510488],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001530103,0.00003453727,0.0000622774,0.00008824794,0.000007652061,0.00007769797,0.0000175401,0.000243924,0.994545,0.0003429782,0.0001443092,0.004282833],"study_design_scores_gemma":[0.00005070725,0.000439332,0.0005586918,0.000004892435,0.00001497011,0.000114171,0.00001019484,0.0004471464,0.9912183,0.00004292652,0.007088143,0.00001050908],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9414098,0.002586993,0.03408293,0.0001645616,0.0001516691,0.0005230519,0.002485186,0.0004726314,0.01812326],"genre_scores_gemma":[0.9316599,0.002400611,0.03878139,0.0001800261,0.00005017522,0.0003840537,0.003844286,0.0001973355,0.02250221],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00354281,"threshold_uncertainty_score":0.01185191,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008107747999508358,"score_gpt":0.2633749445459596,"score_spread":0.2552671965464512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}