{"id":"W2027154313","doi":"10.1097/fjc.0b013e3181f50a70","title":"Redox Regulation of Myocardial Erk 1/2 Phosphorylation in Experimental Hyperthyroidism: Role of Thioredoxin-Peroxiredoxin System","year":2010,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Redox biology and oxidative stress","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Lakehead University","funders":"","keywords":"Peroxiredoxin; Kinase; Thioredoxin; MAPK/ERK pathway; Internal medicine; Endocrinology; Glutathione peroxidase; Glutathione; Antioxidant; Extracellular; Chemistry; Oxidative stress; p38 mitogen-activated protein kinases; Medicine; Peroxidase; Biochemistry; Enzyme; Superoxide dismutase","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002017017,0.0003669369,0.0003131635,0.0001848838,0.0001816629,0.000143741,0.0001704591,0.0002772096,0.0008641483],"category_scores_gemma":[0.0001165355,0.0001311162,0.0003179977,0.0001121202,0.0002963615,0.0003174903,0.0002102695,0.0004826075,0.00007874126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002163977,"about_ca_system_score_gemma":0.0001696898,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002558156,"about_ca_topic_score_gemma":0.0004952052,"domain_scores_codex":[0.9999167,0.00002229344,0.000007332137,0.00001843496,0.00001405788,0.00002108925],"domain_scores_gemma":[0.9999244,0.000005833916,0.00002815294,0.000007386107,0.00001066288,0.00002366243],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004011013,0.0001892752,0.001285998,0.0001466077,0.00002949594,0.0001254597,0.00006419934,0.00006231493,0.9913328,0.00008761588,0.00002979406,0.002635365],"study_design_scores_gemma":[0.0004900162,0.006789022,0.06078157,0.00002640374,0.000195268,0.0008567702,0.0003508453,0.001454718,0.9268416,0.0004115853,0.001776544,0.00002569126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959397,0.002803738,0.0007871118,0.00007990047,0.00002033014,0.00002392152,0.00004464409,0.00001228116,0.0002883746],"genre_scores_gemma":[0.9959953,0.001711404,0.0009784467,0.00005097341,0.00001829906,0.00006861649,0.0001174397,0.000004041096,0.001055553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008641483,"threshold_uncertainty_score":0.002890885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004350127280581234,"score_gpt":0.2393597640666946,"score_spread":0.2350096367861134,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}