{"id":"W2027260613","doi":"10.1016/s1499-2671(08)24028-1","title":"Attenuation of Hepatic Leptin Signalling Leads to Improved Glucose Tolerance.","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Leptin; Endocrinology; Internal medicine; Triglyceride; Medicine; Leptin receptor; Insulin; Hormone; Cholesterol; Obesity","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001812374,0.0004106651,0.0005309,0.0002917854,0.0002581169,0.0006061594,0.0004069028,0.0003813954,0.004288912],"category_scores_gemma":[0.0002152285,0.0002376081,0.0002741009,0.000280937,0.0006009185,0.0002765492,0.00032833,0.001362915,0.0008418166],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000498732,"about_ca_system_score_gemma":0.0005983867,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003043519,"about_ca_topic_score_gemma":0.006183808,"domain_scores_codex":[0.9998264,0.00002399688,0.00001174611,0.00002995331,0.00004438915,0.00006353119],"domain_scores_gemma":[0.999878,0.0000111932,0.00003745785,0.00001534863,0.00001110261,0.00004682607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005581675,0.0004141099,0.0004529317,0.0001740437,0.0000516836,0.0001693021,0.00003586115,0.0001691901,0.9720371,0.0006380491,0.001215437,0.01906079],"study_design_scores_gemma":[0.001402077,0.005816086,0.01958848,0.00008184348,0.00021562,0.0006968727,0.0003188034,0.001663099,0.9511747,0.00115307,0.01784114,0.00004817932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793878,0.007283624,0.004075086,0.001461695,0.0004469317,0.00006898453,0.0009014659,0.0004606438,0.005913829],"genre_scores_gemma":[0.9857697,0.004827435,0.001572325,0.000258987,0.00004287743,0.00006238076,0.0006846096,0.00009183968,0.006689726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004288912,"threshold_uncertainty_score":0.01434785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02234126750548309,"score_gpt":0.2256578164587716,"score_spread":0.2033165489532885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}