{"id":"W2027291775","doi":"10.1038/modpathol.2015.2","title":"Overdiagnosis of high-grade dysplasia in Barrett's esophagus: a multicenter, international study","year":2015,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Esophageal Cancer Research and Treatment","field":"Medicine","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"London Health Sciences Centre","funders":"","keywords":"Overdiagnosis; Medicine; Barrett's esophagus; Dysplasia; Esophagus; Pathology; Multicenter study; General surgery; Radiology; Internal medicine; Adenocarcinoma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002548165,0.0001258644,0.000341304,0.0002172688,0.00001258753,0.00000610275,0.0001306263,0.00006860245,0.00006824089],"category_scores_gemma":[0.0001722549,0.0001072511,0.00005185597,0.0001089135,0.00006982776,0.00006301814,0.0001049463,0.0001783613,0.00003136252],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00023673,"about_ca_system_score_gemma":0.0001119532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005741889,"about_ca_topic_score_gemma":0.0003426932,"domain_scores_codex":[0.9986627,0.0001271768,0.0002697655,0.0003136887,0.0003762422,0.0002504532],"domain_scores_gemma":[0.9993195,0.00006125036,0.00006221385,0.0002778458,0.000107288,0.000171909],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008193187,0.003235938,0.9854409,0.00001805181,0.0001272396,0.004781389,0.002316358,0.00007616181,0.00008534604,0.00006073319,0.0002235635,0.002815044],"study_design_scores_gemma":[0.01837825,0.002741573,0.9729151,0.00004128844,0.00007523152,0.000120753,0.0004765394,0.001615147,0.002606616,0.0009198869,0.0000165852,0.00009302813],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928666,0.004919607,0.0001566214,0.0009415611,0.0002441298,0.0006493467,0.00003045872,0.00002332342,0.0001682909],"genre_scores_gemma":[0.9988649,0.00005210746,0.000528619,0.0001463849,0.00006788294,0.0001661952,0.00003110047,0.00001672149,0.0001260719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01755893,"threshold_uncertainty_score":0.4373571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0407174233111715,"score_gpt":0.3478581126307691,"score_spread":0.3071406893195976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}