{"id":"W2027330531","doi":"10.1016/j.jmb.2007.01.033","title":"Crystal Structure of N-acetyl-γ-glutamyl-phosphate Reductase from Mycobacterium tuberculosis in Complex with NADP+","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":22,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cofactor; Stereochemistry; Chemistry; Active site; Reductase; Enzyme; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000317103,0.0001652943,0.0004192545,0.0001669199,0.00002803597,0.00001434247,0.0002109901,0.000168496,0.0005053535],"category_scores_gemma":[0.00005614613,0.0001170962,0.00008376782,0.0001958811,0.0001686844,0.00009657409,0.0000410143,0.0002262128,0.000002306213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005265128,"about_ca_system_score_gemma":0.0000723493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001520368,"about_ca_topic_score_gemma":0.0001371612,"domain_scores_codex":[0.9986174,0.0001262681,0.0006016261,0.0001965095,0.0001841661,0.0002740404],"domain_scores_gemma":[0.9989617,0.00004882802,0.0005231372,0.0001931281,0.0001777786,0.0000954373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007267525,0.00002818365,0.003072888,0.00001240749,0.00004240653,0.0001167612,0.0001577659,0.0001221345,0.9951103,0.000169363,0.00009339935,0.0003476448],"study_design_scores_gemma":[0.001003034,0.0008055198,0.02254039,0.00003572572,0.00004657858,0.0002947483,0.0001146016,0.000004604986,0.9728884,0.001452651,0.0006776369,0.0001361211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933595,0.0004664662,0.005262941,0.000134934,0.000500454,0.00007605869,0.00009225742,0.000006226703,0.0001011486],"genre_scores_gemma":[0.9885331,0.00001748326,0.01104596,0.000189114,0.0001638731,2.816458e-7,0.00003273451,0.00001412311,0.000003278211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02222191,"threshold_uncertainty_score":0.5533266,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007020678414616066,"score_gpt":0.2450521282477013,"score_spread":0.2380314498330852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}