{"id":"W2027385673","doi":"10.1038/gt.2009.60","title":"Chitosan–plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies","year":2009,"lang":"en","type":"article","venue":"Gene Therapy","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"ca_institutions":"Polytechnique Montréal","funders":"Canadian Institutes of Health Research","keywords":"Recombinant DNA; Gene delivery; Chitosan; Genetic enhancement; Glucosamine; DNA vaccination; Molecular biology; Growth factor; Biology; Chemistry; Biochemistry; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002565709,0.0004911115,0.0002161225,0.000352651,0.0002494705,0.0003008357,0.0002323202,0.0003760348,0.001896711],"category_scores_gemma":[0.0002507553,0.0001865279,0.000293653,0.0003568711,0.0002457366,0.0002165232,0.0001533319,0.0004958511,0.0004599101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007279526,"about_ca_system_score_gemma":0.0004716775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002307466,"about_ca_topic_score_gemma":0.005267772,"domain_scores_codex":[0.9998593,0.00001382032,0.00001118305,0.00002955832,0.00005225587,0.00003386816],"domain_scores_gemma":[0.9998847,0.00003101973,0.00002905016,0.00001280353,0.00002863018,0.00001379844],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004186542,0.0000125707,0.00002526218,0.00005298466,0.000004955369,0.00002350747,0.00001297552,0.00008767784,0.997116,0.0002001923,0.0001127243,0.002309331],"study_design_scores_gemma":[0.000009373733,0.00006479718,0.000147843,0.000002375903,0.00001372724,0.00004573735,0.0000037195,0.0004231987,0.9971977,0.00001902575,0.002069048,0.000003493014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8933499,0.003626691,0.08802633,0.0004440556,0.0002804057,0.0004581326,0.0005640036,0.000553358,0.01269704],"genre_scores_gemma":[0.9419335,0.00169437,0.04039417,0.0001503945,0.00003603625,0.0002052272,0.0005890852,0.0001198914,0.01487736],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002307466,"threshold_uncertainty_score":0.006345153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03930853655444874,"score_gpt":0.2868443076090782,"score_spread":0.2475357710546295,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}