{"id":"W2027392116","doi":"10.1074/jbc.m803116200","title":"An Interaction between the Human T Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor (HBZ) and the KIX Domain of p300/CBP Contributes to the Down-regulation of Tax-dependent Viral Transcription by HBZ","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"CREB; bZIP domain; Leucine zipper; Transactivation; Transcription factor; Activating transcription factor; Basic helix-loop-helix leucine zipper transcription factors; Transcription (linguistics); Activating transcription factor 2; Biology; CREB-binding protein; Zipper; DNA-binding protein; Cell biology; ATF3; P300-CBP Transcription Factors; Genetics; Promoter; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007761741,0.0004032968,0.0002502385,0.0001720133,0.0001861086,0.0003470405,0.0002754716,0.0002458854,0.001381448],"category_scores_gemma":[0.0001139411,0.0001855092,0.0002727682,0.00009228534,0.0002226351,0.0001724013,0.0003181624,0.0005440623,0.0005940279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00045833,"about_ca_system_score_gemma":0.0001834061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009605386,"about_ca_topic_score_gemma":0.001088924,"domain_scores_codex":[0.99989,0.00001264268,0.000004374012,0.00002094394,0.00002950554,0.00004251911],"domain_scores_gemma":[0.9999349,0.000008443079,0.00001910403,0.00000384493,0.000004148944,0.00002952581],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001215489,0.00003562243,0.0002895298,0.00002303874,0.000006908134,0.00009125058,0.000008710891,0.00006158404,0.9981247,0.0000976205,0.0000349757,0.001104568],"study_design_scores_gemma":[0.0001153275,0.0003116578,0.03332682,0.00001093108,0.00004174074,0.00135249,0.0000462958,0.00649008,0.9540984,0.000166488,0.004026999,0.00001269459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948389,0.002091788,0.001986338,0.00007024889,0.00001556467,0.00001678723,0.00006687527,0.00006123648,0.0008523625],"genre_scores_gemma":[0.9964619,0.0006390652,0.0009097195,0.00004007108,0.00001588549,0.00001916832,0.0001902552,0.000009380028,0.001714431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001381448,"threshold_uncertainty_score":0.004621446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01848411436948489,"score_gpt":0.2412341398661335,"score_spread":0.2227500254966486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}