{"id":"W2027392116","doi":"10.1074/jbc.m803116200","title":"An Interaction between the Human T Cell Leukemia Virus Type 1 Basic Leucine Zipper Factor (HBZ) and the KIX Domain of p300/CBP Contributes to the Down-regulation of Tax-dependent Viral Transcription by HBZ","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"T-cell and Retrovirus Studies","field":"Immunology and Microbiology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"CREB; bZIP domain; Leucine zipper; Transactivation; Transcription factor; Activating transcription factor; Basic helix-loop-helix leucine zipper transcription factors; Transcription (linguistics); Activating transcription factor 2; Biology; CREB-binding protein; Zipper; DNA-binding protein; Cell biology; ATF3; P300-CBP Transcription Factors; Genetics; Promoter; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004332255,0.0001468393,0.0003916754,0.00002141006,0.0002722771,0.000008341181,0.0002540066,0.000231881,0.0001113739],"category_scores_gemma":[0.00006287693,0.0000583384,0.0001367414,0.00007095856,0.0006239921,0.00005059252,0.00004426231,0.0004396845,0.000002860422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005629355,"about_ca_system_score_gemma":0.00002560354,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001020154,"about_ca_topic_score_gemma":0.00000730079,"domain_scores_codex":[0.9988912,0.0002384346,0.0005145596,0.0001338368,0.00006657637,0.0001553599],"domain_scores_gemma":[0.9990046,0.000238784,0.0004505559,0.0001477156,0.0001364714,0.00002186639],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007948322,0.00008662004,0.007717133,0.0000122293,0.0001543203,6.293803e-7,0.0004231612,0.00001063547,0.9896651,0.00001771188,0.0007534069,0.0003642413],"study_design_scores_gemma":[0.001733346,0.0004526381,0.0584908,0.00002198243,0.00007616267,0.00004021867,0.000517228,9.807102e-7,0.9352174,0.0001789215,0.003193439,0.00007681999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953457,0.003364901,0.0001649523,0.0006161393,0.0001511997,0.0001339716,0.00008992395,0.000005691555,0.0001275291],"genre_scores_gemma":[0.9990583,0.000436968,0.00001005898,0.00007587867,0.0001155128,0.000003000637,0.0000323595,0.000004682394,0.0002632151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05444762,"threshold_uncertainty_score":0.2378971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01848411436948489,"score_gpt":0.2412341398661335,"score_spread":0.2227500254966486,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}