{"id":"W2027397876","doi":"10.1385/mn:24:1-3:107","title":"Molecular Mechanisms of Glutamate Receptor-Mediated Excitotoxic Neuronal Cell Death","year":2001,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":540,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Kainate receptor; Excitotoxicity; AMPA receptor; Glutamate receptor; NMDA receptor; Neuroscience; Metabotropic glutamate receptor 1; Biology; Metabotropic glutamate receptor; Programmed cell death; Kainic acid; Receptor; Metabotropic glutamate receptor 6; Cell biology; Pharmacology; Biochemistry; Apoptosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.000443191,0.00131026,0.002912755,0.001148212,0.0002373904,0.00007112008,0.002999634,0.0008752916,0.0003746206],"category_scores_gemma":[0.0009334435,0.001179675,0.001171556,0.002465233,0.0009208307,0.000137169,0.001203611,0.002124154,0.0009747962],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007872179,"about_ca_system_score_gemma":0.0006149117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005161431,"about_ca_topic_score_gemma":2.098869e-7,"domain_scores_codex":[0.9883857,0.004605297,0.001546717,0.002824069,0.0007801254,0.001858031],"domain_scores_gemma":[0.9955905,0.001327859,0.00104862,0.001424929,0.0001133383,0.0004947298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003704395,0.0004026218,5.524709e-7,0.001664675,0.0000204748,0.004168756,0.000004815687,0.00001792977,0.9845138,0.0009558461,0.00020455,0.008008976],"study_design_scores_gemma":[0.000555572,0.0009784193,7.471788e-7,0.0003193089,0.0001933152,0.0009748235,0.000001025569,0.0000321079,0.646668,0.0002313764,0.3492803,0.0007650582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09489651,0.8826454,0.001615996,0.0003111408,0.006528163,0.007786314,0.001245501,0.0009098667,0.004061129],"genre_scores_gemma":[0.006615227,0.9894424,0.00005372017,0.00269718,0.00007013461,0.0002814919,0.0000594455,0.000335084,0.0004453079],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.3490757,"threshold_uncertainty_score":0.9999649,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05855761855224767,"score_gpt":0.3454298673297866,"score_spread":0.286872248777539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}