{"id":"W2027410299","doi":"10.1523/jneurosci.5747-08.2009","title":"BNIP3 (Bcl-2 19 kDa Interacting Protein) Acts as Transcriptional Repressor of Apoptosis-Inducing Factor Expression Preventing Cell Death in Human Malignant Gliomas","year":2009,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Cancer Institute; Canadian Institutes of Health Research; Terry Fox Foundation; CancerCare Manitoba Foundation","keywords":"Repressor; Psychological repression; Apoptosis; Programmed cell death; Biology; Cancer research; Histone deacetylase; Nuclear protein; HDAC1; Cell biology; Glioma; Regulation of gene expression; Histone; Gene expression; Molecular biology; Transcription factor; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006084442,0.0002247539,0.0001224653,0.0001462267,0.0001174576,0.0001544006,0.0000865338,0.00009768363,0.0007915677],"category_scores_gemma":[0.00007660078,0.000072248,0.0001132217,0.0001244205,0.0001609867,0.00008939152,0.0001645069,0.000248854,0.0003448926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002452647,"about_ca_system_score_gemma":0.0001443287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007239442,"about_ca_topic_score_gemma":0.0008041281,"domain_scores_codex":[0.9999589,0.000006249647,0.000002675183,0.000006734466,0.00001297498,0.00001247305],"domain_scores_gemma":[0.9999648,0.000004281317,0.00001130858,0.000003088002,0.00000450293,0.00001191359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001479223,0.00001311381,0.0007032599,0.00003173644,0.000004773092,0.00007790314,0.000007020202,0.00004251007,0.9968899,0.00005591788,0.00005583284,0.001970101],"study_design_scores_gemma":[0.00006248472,0.0003017838,0.03543338,0.00000924671,0.00003148588,0.001779656,0.00003958104,0.001249598,0.9566953,0.0002251713,0.004165986,0.000006292385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925647,0.003766842,0.001961205,0.00009932822,0.00001335794,0.0000140385,0.0002916931,0.00007355461,0.001215281],"genre_scores_gemma":[0.9956374,0.00150586,0.001187605,0.00004070055,0.000006334243,0.0000141707,0.0006915041,0.00001347492,0.0009031372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007915677,"threshold_uncertainty_score":0.002648115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02725209931640642,"score_gpt":0.2934318850123034,"score_spread":0.266179785695897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}