{"id":"W2027416732","doi":"10.1212/01.wnl.0000296811.19811.db","title":"Genetics of familial amyotrophic lateral sclerosis","year":2008,"lang":"en","type":"review","venue":"Neurology","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":277,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame","funders":"","keywords":"Amyotrophic lateral sclerosis; SOD1; Genetics; C9orf72; Disease; Biology; Identification (biology); Genetic epidemiology; Gene; Mutation; Medicine; Trinucleotide repeat expansion; Allele; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002031393,0.0007242289,0.0003965362,0.001107174,0.0007500226,0.0005373122,0.0002253502,0.0009307971,0.00371105],"category_scores_gemma":[0.0004721329,0.0001515664,0.0002460104,0.001029416,0.0006438261,0.0003920597,0.000461715,0.0004526279,0.0009877868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006460426,"about_ca_system_score_gemma":0.0004475496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003264858,"about_ca_topic_score_gemma":0.003379292,"domain_scores_codex":[0.9998087,0.00004359808,0.00002034406,0.00004081896,0.00006308882,0.00002342422],"domain_scores_gemma":[0.9998524,0.00003885848,0.00005557595,0.000006423986,0.00001958827,0.00002723047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008493609,0.0002267178,0.1563193,0.001413497,0.0004743015,0.2252761,0.005383926,0.001682487,0.1015335,0.0745225,0.1306575,0.3016609],"study_design_scores_gemma":[0.000171573,0.0002463241,0.2650882,0.001530675,0.0004219692,0.3331247,0.001502331,0.001502152,0.005464821,0.0483598,0.3424583,0.0001292],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.6148154,0.1613545,0.01076055,0.02316376,0.001947551,0.0002206824,0.002799187,0.001264477,0.1836738],"genre_scores_gemma":[0.9255717,0.03943773,0.004696356,0.002994415,0.001034222,0.00008783951,0.001350056,0.0001000034,0.02472773],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00371105,"threshold_uncertainty_score":0.01241469,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1147889839078635,"score_gpt":0.3474581027037291,"score_spread":0.2326691187958656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}