{"id":"W2027436185","doi":"10.3389/fnagi.2014.00053","title":"Differential role of CSF alpha-synuclein species, tau, and Aβ42 in Parkinson's Disease","year":2014,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Parkinson's Disease Mechanisms and Treatments","field":"Medicine","cited_by":172,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Cerebrospinal fluid; Montreal Cognitive Assessment; Parkinson's disease; Internal medicine; Cognitive decline; Cognitive impairment; Gastroenterology; Medicine; Oncology; Biomarker; Alpha-synuclein; Disease; Psychology; Dementia; Chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007342061,0.0004900143,0.0004955827,0.001476858,0.000366888,0.000718712,0.0002193098,0.0005587616,0.0006160837],"category_scores_gemma":[0.002301193,0.0003250107,0.0002518563,0.0005513733,0.0004461644,0.0004518989,0.0003620939,0.0002553074,0.0002161369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002404351,"about_ca_system_score_gemma":0.0001710027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009935427,"about_ca_topic_score_gemma":0.0007867253,"domain_scores_codex":[0.9996271,0.00007207572,0.00007484861,0.00009738369,0.00008401502,0.00004455592],"domain_scores_gemma":[0.9990972,0.0003240886,0.0002401514,0.00004258722,0.0001252592,0.0001707022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001528628,0.00007320505,0.9853308,0.00003251197,0.00007467929,0.001009474,0.000192034,0.00008573863,0.005293468,0.00001804408,0.00004371165,0.006317616],"study_design_scores_gemma":[0.00001841366,0.0003547962,0.9962908,0.000009090863,0.00005405148,0.001874789,0.0001467297,0.0002260839,0.0007879884,0.00006387531,0.0001675319,0.000005889553],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986318,0.001080911,0.0000654509,0.000008082959,0.000006394043,0.000004032264,0.00004173406,0.000003540649,0.0001580409],"genre_scores_gemma":[0.9995395,0.000212365,0.00008054689,0.000009749329,0.00001020019,0.000003624698,0.0000678828,0.000001027823,0.00007512056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001476858,"threshold_uncertainty_score":0.003882945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01079963780943489,"score_gpt":0.2283162944676733,"score_spread":0.2175166566582384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}