{"id":"W2027513185","doi":"10.1016/s0168-3659(01)00265-6","title":"Tissue engineering as a platform for controlled release of therapeutic agents: implantation of microencapsulated dopamine producing cells in the brains of rats","year":2001,"lang":"en","type":"article","venue":"Journal of Controlled Release","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Medical Research Council","keywords":"Biomedical engineering; Tissue engineering; Drug delivery; Regenerative medicine; Controlled release; Insulin delivery; Cannula; Dopamine; Cell; Computer science; Nanotechnology; Chemistry; Medicine; Pharmacology; Neuroscience; Biology; Materials science; Surgery; Biochemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001207545,0.0001834442,0.001439661,0.000433363,0.0000256994,0.000008739354,0.0001206455,0.0000876447,0.00005879971],"category_scores_gemma":[0.001923684,0.0001112385,0.0003672404,0.0003186036,0.00004130266,0.0001114856,0.000006631262,0.0002063271,0.000001107585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004919863,"about_ca_system_score_gemma":0.0002349597,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003599649,"about_ca_topic_score_gemma":0.000002487215,"domain_scores_codex":[0.9976544,0.0001013769,0.001519401,0.0001222981,0.0003848355,0.0002176436],"domain_scores_gemma":[0.9965717,0.001209124,0.001323577,0.0002158424,0.0005774404,0.0001023217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.04402283,0.0006637843,0.000547185,0.0003203267,0.0007011027,0.00007702287,0.0008355887,0.00221787,0.9478776,0.00006548534,0.0001452475,0.002525893],"study_design_scores_gemma":[0.294352,0.006247316,0.00738545,0.001764473,0.002974973,0.0006181116,0.001510183,0.02775641,0.6559972,0.0002159848,0.0009007524,0.0002772297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943827,0.001955861,0.001022346,0.0004837871,0.0001734743,0.001766706,0.00001163539,0.000006297828,0.0001971969],"genre_scores_gemma":[0.9986038,0.0003655934,0.0003494493,0.0002534918,0.0001257641,0.00002749894,0.000007538072,0.00001914386,0.0002477744],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2918805,"threshold_uncertainty_score":0.4536176,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01473326474465617,"score_gpt":0.2716914417430988,"score_spread":0.2569581769984426,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}