{"id":"W2027556747","doi":"10.2174/156800910791859452","title":"Antisense Treatment in Human Prostate Cancer and Melanoma","year":2010,"lang":"en","type":"review","venue":"Current Cancer Drug Targets","topic":"Clusterin in disease pathology","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Victoria Hospital; Western University","funders":"Canadian Institutes of Health Research; Francis Crick Institute","keywords":"Prostate cancer; Antisense therapy; Clusterin; Cancer; Cancer research; RNA; Medicine; Prostate; Biology; Internal medicine; Gene; Apoptosis; Locked nucleic acid; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001255591,0.0007007988,0.002265143,0.0003530004,0.00008035255,0.00002517221,0.0001335288,0.0002487434,0.000332563],"category_scores_gemma":[0.00002446722,0.0005400537,0.0003112754,0.0002158262,0.0002024542,0.00004731007,0.000151108,0.000712981,0.00002446925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008238391,"about_ca_system_score_gemma":0.0008969108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004984402,"about_ca_topic_score_gemma":0.001417124,"domain_scores_codex":[0.9974715,0.0001238648,0.0007056222,0.0009136544,0.0002114484,0.0005739427],"domain_scores_gemma":[0.9986181,0.00005976175,0.0003534212,0.0005668476,0.00006630158,0.0003355325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000329223,0.0002765661,0.005272986,0.0176127,0.0001117098,0.000300242,0.0004580533,2.861424e-7,0.00001083047,0.000008264959,0.001219788,0.9746956],"study_design_scores_gemma":[0.001637279,0.00007395347,0.00148802,0.0174007,0.001395521,0.00008591294,0.000008541989,0.00000426311,0.00001403774,0.00001561844,0.9774153,0.0004608534],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01558462,0.9779567,1.570029e-7,0.0001563461,0.002454985,0.00280731,0.000828857,0.00006112631,0.0001498794],"genre_scores_gemma":[0.0003335857,0.9942616,0.00002634556,0.00002972514,0.0007508234,0.002998957,0.0004423303,0.0001111827,0.001045448],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9761955,"threshold_uncertainty_score":0.9997051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05579727939079897,"score_gpt":0.4177648667764648,"score_spread":0.3619675873856658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}