{"id":"W2027592786","doi":"10.1155/2014/262350","title":"Outcome Measures in Relapsing-Remitting Multiple Sclerosis: Capturing Disability and Disease Progression in Clinical Trials","year":2014,"lang":"en","type":"review","venue":"Multiple Sclerosis International","topic":"Health Systems, Economic Evaluations, Quality of Life","field":"Economics, Econometrics and Finance","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Medicine; Multiple sclerosis; Clinical trial; Surrogate endpoint; Clinical endpoint; Disease; Physical therapy; Expanded Disability Status Scale; Physical medicine and rehabilitation; Intensive care medicine; Internal medicine; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.04943715,0.001494632,0.006658248,0.00609831,0.000333827,0.00292735,0.002158662,0.002813318,0.003088292],"category_scores_gemma":[0.09992481,0.0006264496,0.003555361,0.00822972,0.0011509,0.002746821,0.00152326,0.002719045,0.0004109886],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002989088,"about_ca_system_score_gemma":0.005298903,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001506424,"about_ca_topic_score_gemma":0.001819262,"domain_scores_codex":[0.9559726,0.03341078,0.005102428,0.0009174084,0.004276784,0.0003198406],"domain_scores_gemma":[0.9033325,0.08425811,0.008224041,0.0008008971,0.002905976,0.0004784994],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0007600663,0.0001142095,0.00118281,0.2069499,0.005675396,0.00005787844,0.0001438809,0.002091348,0.0001221326,0.01209472,0.007735362,0.7630723],"study_design_scores_gemma":[0.002422502,0.001785953,0.01228467,0.6513313,0.02734678,0.0008832763,0.0005985048,0.006160972,0.0007068202,0.04773654,0.2485148,0.0002279022],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002363085,0.997649,0.0008472351,0.0005492131,0.00009952455,0.0001485525,0.00006613063,0.0000059528,0.0003981016],"genre_scores_gemma":[0.008915585,0.9860005,0.003391698,0.000555555,0.0002266982,0.0006474258,0.0001241975,0.000007650196,0.0001307221],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9505628,"threshold_uncertainty_score":0.2614518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.8246941223373784,"score_gpt":0.554033233052401,"score_spread":0.2706608892849773,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}