{"id":"W2027603142","doi":"10.1074/jbc.m307200200","title":"Protein Interaction Domains of the Ubiquitin-specific Protease, USP7/HAUSP","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"National Cancer Institute","keywords":"Peptide; Ubiquitin; Chemistry; Dissociation constant; Proteolysis; Protease; Biochemistry; Molecular biology; Biology; Enzyme; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005145118,0.0001630528,0.0002278077,0.00001476666,0.00006767242,0.00001604227,0.0003370469,0.0002635624,0.0002161777],"category_scores_gemma":[0.0004857503,0.00009674723,0.0002904933,0.0001040991,0.0001787434,0.000005416237,0.0000798589,0.0003385764,0.000002715961],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002657776,"about_ca_system_score_gemma":0.0001006217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":6.618881e-7,"about_ca_topic_score_gemma":2.220788e-7,"domain_scores_codex":[0.9987525,0.0001651406,0.0004990916,0.0001906431,0.0001895119,0.0002031021],"domain_scores_gemma":[0.9988036,0.00002240991,0.0005972833,0.0002797573,0.0002012532,0.00009576797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001730104,0.0001349776,0.001098935,0.00003647966,0.00003427476,0.000005226041,0.00001286664,0.000005426965,0.9974531,0.0001207381,0.0004170492,0.0005079226],"study_design_scores_gemma":[0.000441335,0.0002701367,0.0004367603,0.00007390796,0.000007474097,0.0002315759,0.0001044971,6.248895e-7,0.9251683,0.0003979452,0.0727524,0.0001150963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928293,0.0007700603,0.0002481678,0.0001145128,0.0001208857,0.0002285835,0.00001320172,0.000004214598,0.005671033],"genre_scores_gemma":[0.9982823,0.0001141857,0.0008099411,0.00006901623,0.0003189683,0.00001512784,0.000006236965,0.00001056582,0.0003736448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07233535,"threshold_uncertainty_score":0.3945238,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02656694316748175,"score_gpt":0.2533145057323229,"score_spread":0.2267475625648412,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}