{"id":"W2027625151","doi":"10.1002/eji.201040340","title":"HCV‐specific T cells in HCV/HIV co‐infection show elevated frequencies of dual Tim‐3/PD‐1 expression that correlate with liver disease progression","year":2010,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Michael's Hospital; Maple Leaf Medical Clinic; McGill University Health Centre; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario HIV Treatment Network; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Hepatitis C virus; Biology; Immunology; CD8; Immune system; T cell; Cytotoxic T cell; Virology; Antibody; Virus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009397548,0.0002121393,0.0002980207,0.0003396727,0.0002239681,0.0002734947,0.00008490216,0.0002882569,0.001945258],"category_scores_gemma":[0.0002047438,0.0001593012,0.0001508678,0.0002353215,0.0001613251,0.0001487987,0.0002654929,0.0004991526,0.0004191567],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001422835,"about_ca_system_score_gemma":0.0001165838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003589605,"about_ca_topic_score_gemma":0.0004312203,"domain_scores_codex":[0.999838,0.00001757023,0.00001760723,0.00003795948,0.00002891531,0.00005989488],"domain_scores_gemma":[0.9997969,0.00002741761,0.0000561284,0.00001737207,0.00002119059,0.00008095952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001328818,0.0001109408,0.02581736,0.00007258565,0.00001873716,0.0005518451,0.0001441265,0.00006901458,0.9673821,0.00005151926,0.00007998834,0.004373125],"study_design_scores_gemma":[0.00006505073,0.002511361,0.7531832,0.00002698581,0.0001237967,0.009034673,0.0004229308,0.001462786,0.230525,0.0002054195,0.002409727,0.00002911211],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986088,0.0004947902,0.0002685683,0.00001022206,0.000007429508,0.00001549101,0.0001000205,0.00001378214,0.0004810306],"genre_scores_gemma":[0.9985247,0.0001843663,0.0002758208,0.00002989783,0.00001259545,0.0000367779,0.0002291866,0.0000047617,0.0007018262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001945258,"threshold_uncertainty_score":0.006507516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01214737921415574,"score_gpt":0.2153991912039162,"score_spread":0.2032518119897605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}