{"id":"W2027651583","doi":"10.1002/ddr.10300","title":"Proteinase‐activated receptors (PARs): An evolving hormonal system","year":2003,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Blood Coagulation and Thrombosis Mechanisms","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Servier; Kidney Foundation of Canada","keywords":"Receptor; G protein-coupled receptor; Drug discovery; Molecular Pharmacology; Biology; Drug development; Signal transduction; Thrombin; Hormone; Neuroscience; Computational biology; Cell biology; Drug; Pharmacology; Bioinformatics; Biochemistry; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003192876,0.0001937447,0.0002995338,0.0004555725,0.0004944184,0.00009644012,0.000168331,0.0001228488,0.0008276262],"category_scores_gemma":[0.0002807255,0.0001686301,0.00004677048,0.000866059,0.00006713469,0.0002098108,0.0000678029,0.0005243749,0.0004490269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005686051,"about_ca_system_score_gemma":0.001039547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003207986,"about_ca_topic_score_gemma":0.00001222234,"domain_scores_codex":[0.9964474,0.0005303571,0.0003928032,0.0004920291,0.001460481,0.0006769397],"domain_scores_gemma":[0.9983063,0.0000788711,0.00005891525,0.0003933285,0.0007219143,0.0004406757],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007772726,0.003625326,0.0312078,0.001868952,0.000923512,0.0004479889,0.01049152,0.000013637,0.772912,0.1106286,0.02294858,0.04415477],"study_design_scores_gemma":[0.001853282,0.0002275259,0.01640599,0.0005104196,0.00001804648,0.00007190397,0.004238349,0.0002643457,0.9234029,0.0001740395,0.05246789,0.0003653205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9693314,0.0001580816,0.0003349419,0.0003518843,0.0002249175,0.001509357,0.000001051288,0.0002615848,0.02782671],"genre_scores_gemma":[0.9822229,0.000007299146,0.01224772,0.0000488101,0.00006343828,0.0002282017,0.00005882983,0.00004387144,0.00507899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1504908,"threshold_uncertainty_score":0.9061926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08806677892082602,"score_gpt":0.351769653228645,"score_spread":0.263702874307819,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}