{"id":"W2027655328","doi":"10.1097/fjc.0b013e31821823f5","title":"Stem Cells for Drug Screening","year":2011,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Induced pluripotent stem cell; Cardiotoxicity; Embryonic stem cell; Stem cell; Drug; Drug discovery; Medicine; Pharmacology; Human Induced Pluripotent Stem Cells; Drug toxicity; Biology; Bioinformatics; Toxicity; Cell biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001654263,0.0001546578,0.0004059639,0.0001309827,0.00007150742,0.00001083362,0.0004477163,0.0001211128,0.00004778115],"category_scores_gemma":[0.00001123574,0.0001393647,0.001227407,0.00008406273,0.00008053472,0.000009701803,0.0001238329,0.0002011597,0.000008104038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002135741,"about_ca_system_score_gemma":0.0001261207,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004779713,"about_ca_topic_score_gemma":5.448875e-7,"domain_scores_codex":[0.9983844,0.000293607,0.0003983684,0.0002332054,0.0003225781,0.00036791],"domain_scores_gemma":[0.9988862,0.00002969898,0.0001973685,0.0002515121,0.0004553289,0.0001798791],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008897533,0.0001261884,0.0001433185,0.00007712832,0.006333161,0.0001559909,0.0001119834,0.001833457,0.9343143,0.00000738806,0.03237546,0.02363184],"study_design_scores_gemma":[0.001831332,0.0002835107,0.00005744124,0.000006667001,0.000382868,0.0002052304,0.00005524734,0.00006003881,0.6877788,0.00001092297,0.3092135,0.0001144082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8153461,0.03245565,0.1469012,0.000124223,0.002688694,0.0008076223,0.00002428804,0.00001297895,0.001639227],"genre_scores_gemma":[0.9885029,0.00222633,0.006708125,0.0002138007,0.001435644,0.00002579075,0.000004409006,0.00005043965,0.0008325937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2768381,"threshold_uncertainty_score":0.5683128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03650911961342472,"score_gpt":0.2827566336515418,"score_spread":0.2462475140381171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}