{"id":"W2027825593","doi":"10.1002/iub.164","title":"Age‐associated mitochondrial dysfunction in skeletal muscle: Contributing factors and suggestions for long‐term interventions","year":2009,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"","keywords":"Mitochondrial biogenesis; Skeletal muscle; Mitochondrion; Sarcopenia; Biology; Reactive oxygen species; Biogenesis; Organelle biogenesis; Cell biology; Function (biology); Internal medicine; Endocrinology; Medicine; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001678187,0.0001516157,0.0001955308,0.00008262991,0.0001374851,0.00003602849,0.00007042386,0.0002505948,0.0000324231],"category_scores_gemma":[0.001369038,0.0001487654,0.0001684678,0.00009898285,0.00004571593,0.000007883593,0.00003094234,0.0001216332,0.000003037426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000024626,"about_ca_system_score_gemma":0.00004071302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001606593,"about_ca_topic_score_gemma":0.0004628284,"domain_scores_codex":[0.9989104,0.0001005176,0.0003082572,0.0003231279,0.00006722933,0.0002905005],"domain_scores_gemma":[0.9994997,0.00005063518,0.0001089488,0.0001479805,0.00008224292,0.0001104278],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004919968,0.00101697,0.1996154,0.00008777218,0.0002204449,0.00002854743,0.0003827942,0.00009404967,0.7632884,0.001271405,0.01116848,0.02233369],"study_design_scores_gemma":[0.004521858,0.001081426,0.9781201,0.00007838689,0.00008111256,0.00001106005,0.0000799695,0.00004523517,0.005035735,0.0002294401,0.01036313,0.0003525282],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9731768,0.000272887,0.02427779,0.0003326287,0.001226487,0.0004381249,0.00009758836,0.00003064071,0.0001471103],"genre_scores_gemma":[0.9972247,0.00003600246,0.0003423154,0.0002790496,0.0004907681,0.00003798919,0.001039995,0.00001273464,0.0005363785],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7785047,"threshold_uncertainty_score":0.6066476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02287279439499148,"score_gpt":0.2899967834992831,"score_spread":0.2671239891042916,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}