{"id":"W2027849611","doi":"10.1128/mcb.02025-07","title":"A Glycine-Arginine Domain in Control of the Human MRE11 DNA Repair Protein","year":2008,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Rad50; DNA repair; Replication protein A; Nuclease; Cell biology; DNA damage; DNA; Molecular biology; Biochemistry; DNA-binding protein; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009714448,0.0002154721,0.0001385712,0.00006164461,0.000116537,0.0001551042,0.0001059473,0.000160873,0.00109927],"category_scores_gemma":[0.0001093782,0.00009361146,0.0001269876,0.00005533289,0.0001732978,0.00009925471,0.0001629917,0.0002349736,0.0004616019],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002163728,"about_ca_system_score_gemma":0.00007897355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003009622,"about_ca_topic_score_gemma":0.0004608233,"domain_scores_codex":[0.9999233,0.00001746004,0.000004849441,0.00002925965,0.00001304259,0.00001206765],"domain_scores_gemma":[0.999938,0.00001263752,0.00002135502,0.000008317511,0.00000493092,0.00001480833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007478452,0.000003935138,0.0001584085,0.00001158702,0.000001752115,0.00004960432,0.00000772164,0.00007170637,0.9986112,0.0001030005,0.00001378965,0.000892519],"study_design_scores_gemma":[0.0000172532,0.0001440371,0.007460044,0.000004768724,0.00001241009,0.0004449503,0.00002311503,0.001385274,0.9860755,0.00009410363,0.004331471,0.000007028232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992673,0.001903865,0.004014371,0.00009044096,0.00003422478,0.00001204929,0.0001333509,0.00009902636,0.001039647],"genre_scores_gemma":[0.9968531,0.0002815758,0.001360444,0.00002468874,0.000004954342,0.000005403298,0.0001052139,0.00001440076,0.001350247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00109927,"threshold_uncertainty_score":0.003677368,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004389414996553444,"score_gpt":0.2055988836421929,"score_spread":0.2012094686456395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}