{"id":"W2027849611","doi":"10.1128/mcb.02025-07","title":"A Glycine-Arginine Domain in Control of the Human MRE11 DNA Repair Protein","year":2008,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Cancer-related gene regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Rad50; DNA repair; Replication protein A; Nuclease; Cell biology; DNA damage; DNA; Molecular biology; Biochemistry; DNA-binding protein; Gene; Transcription factor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001802274,0.0001608464,0.0002217097,0.00005746163,0.00007752612,0.000002434341,0.0001461635,0.0002587045,0.00001140805],"category_scores_gemma":[0.00003067654,0.0001294666,0.0001474716,0.0001409616,0.0002982861,0.000001827319,0.00009240105,0.00011303,0.000001082439],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001475636,"about_ca_system_score_gemma":0.00005908694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006672652,"about_ca_topic_score_gemma":0.00005313722,"domain_scores_codex":[0.9988232,0.0002193383,0.000295089,0.0003566171,0.00007834159,0.0002273757],"domain_scores_gemma":[0.9993704,0.000004668722,0.0001180869,0.0004178071,0.00004563474,0.00004339424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007161994,0.00004466865,0.008758328,0.00001356952,0.00004958783,0.00001074642,0.00003849581,0.00006401912,0.9898937,0.0008703077,0.00004535815,0.0001395679],"study_design_scores_gemma":[0.002001887,0.0003495805,0.005414545,0.00001823918,0.00001658404,0.00004442152,0.000017631,0.0000720324,0.9854174,0.0005626903,0.00590585,0.0001790878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928024,0.002827311,0.003290199,0.0002127768,0.00006017036,0.0004762474,0.0000111761,0.000011219,0.0003085313],"genre_scores_gemma":[0.9992852,0.00002637021,0.0001731768,0.000110061,0.00006129888,0.00004216929,0.00006752874,0.00001931355,0.0002148874],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006482824,"threshold_uncertainty_score":0.5279493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004389414996553444,"score_gpt":0.2055988836421929,"score_spread":0.2012094686456395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}