{"id":"W2027889680","doi":"10.1002/pbc.22229","title":"2′‐chlorodeoxyadenosine (2‐CdA) as salvage therapy for Langerhans cell histiocytosis (LCH). results of the LCH‐S‐98 protocol of the histiocyte society","year":2009,"lang":"en","type":"article","venue":"Pediatric Blood & Cancer","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":113,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Medicine; Langerhans cell histiocytosis; Histiocyte; Histiocytosis; Salvage therapy; Surgery; Internal medicine; Gastroenterology; Disease; Chemotherapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001354415,0.0005516486,0.0006684331,0.0003289475,0.0002997741,0.0003030476,0.00049735,0.000456598,0.0009011694],"category_scores_gemma":[0.0004616527,0.0001559342,0.0004187895,0.0002368865,0.0003545404,0.0002190885,0.0002851578,0.0006423668,0.0002674101],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005056893,"about_ca_system_score_gemma":0.000747973,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003923775,"about_ca_topic_score_gemma":0.0009477775,"domain_scores_codex":[0.9995129,0.0002970212,0.0000404867,0.00005501304,0.00005479929,0.00003978935],"domain_scores_gemma":[0.999557,0.00009775033,0.0001253927,0.00005612601,0.00003366412,0.0001300928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2462503,0.02176588,0.1173026,0.001606707,0.001127552,0.001541874,0.0005562923,0.007256634,0.190926,0.0004646467,0.00352112,0.4076804],"study_design_scores_gemma":[0.1026566,0.5966366,0.1892979,0.0002686243,0.001089704,0.005488195,0.0001922525,0.003566941,0.08130217,0.0003267395,0.01912446,0.00004976396],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919756,0.003687239,0.0009146867,0.000123846,0.00003149941,0.00188717,0.0003483091,0.00004293024,0.0009888037],"genre_scores_gemma":[0.9922151,0.001399388,0.002537805,0.0002098181,0.00004936239,0.001475961,0.001518185,0.00001004926,0.0005844173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001354415,"threshold_uncertainty_score":0.007162869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399810976776813,"score_gpt":0.2879838772006084,"score_spread":0.2739857674328403,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}