{"id":"W2027969846","doi":"10.1016/j.cardiores.2005.02.005","title":"Angiotensin II-evoked enhanced expression of RGS2 attenuates Gi-mediated adenylyl cyclase signaling in A10 cells","year":2005,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenylyl cyclase; Gs alpha subunit; RGS2; Angiotensin II; Vascular smooth muscle; G protein; Internal medicine; Endocrinology; Cell biology; Signal transduction; Chemistry; ADCY9; Biology; GTPase-activating protein; Receptor; Smooth muscle; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002340794,0.0002010452,0.0004022285,0.0003003519,0.0001552977,0.00002587308,0.0002887509,0.0002986806,0.0000517987],"category_scores_gemma":[0.000430087,0.000196403,0.0005093334,0.0004951438,0.0001942777,0.00001333399,0.0003067822,0.0003275604,0.00003016507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005626159,"about_ca_system_score_gemma":0.0001429062,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004362329,"about_ca_topic_score_gemma":0.000009726805,"domain_scores_codex":[0.9970104,0.000606105,0.0004081368,0.0005970329,0.0008196755,0.0005586622],"domain_scores_gemma":[0.998465,0.00005817045,0.00006943812,0.0007905541,0.0004541666,0.0001626534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001260226,0.00008447286,0.00006028813,0.00004066245,0.0001156334,0.00002153882,0.0001118874,0.01089513,0.9835418,0.000005719694,0.0003660459,0.004630754],"study_design_scores_gemma":[0.001311411,0.0001061003,0.0001668049,0.0001506925,0.00001822916,0.000005680764,0.00009551034,0.000629704,0.9827562,0.00002143149,0.01452628,0.0002119862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855093,0.0118061,0.001639482,0.0001269081,0.00004806551,0.0005411589,0.00001566353,0.00001837684,0.000294947],"genre_scores_gemma":[0.9972677,0.0003955574,0.001455043,0.00003205285,0.0003529293,0.00005383305,0.0001308026,0.00004142364,0.0002706737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01416023,"threshold_uncertainty_score":0.8009083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02621827313507369,"score_gpt":0.2921409119074229,"score_spread":0.2659226387723492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}