{"id":"W2028040523","doi":"10.1039/c2lc40504k","title":"Denaturation mapping of Saccharomyces cerevisiae","year":2012,"lang":"en","type":"article","venue":"Lab on a Chip","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"","keywords":"Optical mapping; Contig; Denaturation (fissile materials); Genome; Saccharomyces cerevisiae; Genomic organization; DNA; Computational biology; Biology; Chemistry; Yeast; Biophysics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009768904,0.0002866064,0.0002529291,0.0004499215,0.0003112843,0.0002522151,0.0001855084,0.0001961316,0.0008102283],"category_scores_gemma":[0.0002745976,0.0001980916,0.0002570383,0.0004176551,0.0001150066,0.0001290754,0.0003269544,0.0003262615,0.0005623209],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005951466,"about_ca_system_score_gemma":0.0003363945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004207125,"about_ca_topic_score_gemma":0.004938198,"domain_scores_codex":[0.9998993,0.00001200808,0.000006942111,0.00003367059,0.00003476853,0.00001329612],"domain_scores_gemma":[0.9999075,0.00002106544,0.00001748798,0.00001666277,0.00002402069,0.00001313097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000053796,0.000007910618,0.0002854647,0.00004304259,0.000002906038,0.00003938296,0.00003216693,0.0003771599,0.9936197,0.0002202353,0.00008805937,0.005230111],"study_design_scores_gemma":[0.000008202603,0.00004060918,0.004948496,0.000008054374,0.000009055474,0.0001474138,0.00003631231,0.00306978,0.9820739,0.0002413153,0.009405681,0.00001115923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9283987,0.002389011,0.05925521,0.0002308395,0.0000706252,0.00009506279,0.002469098,0.0009081399,0.006183336],"genre_scores_gemma":[0.932544,0.001335047,0.05353189,0.0001291187,0.000007805063,0.00008705189,0.004873275,0.000352217,0.007139599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004207125,"threshold_uncertainty_score":0.008365273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01713561535232951,"score_gpt":0.2435573235691469,"score_spread":0.2264217082168174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}