{"id":"W2028065028","doi":"10.1098/rsob.110031","title":"<i>Drosophila</i> poly suggests a novel role for the Elongator complex in insulin receptor–target of rapamycin signalling","year":2012,"lang":"en","type":"article","venue":"Open Biology","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"University of Edinburgh; Natural Sciences and Engineering Research Council of Canada; University College Dublin; British Heart Foundation; Wellcome Trust","keywords":"Biology; Insulin receptor; Cell biology; Insulin; Mutant; Proto-Oncogene Proteins c-akt; TOR signaling; Signal transduction; Protein kinase B; Genetics; Gene; Endocrinology; Insulin resistance","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001624992,0.0002469932,0.0005838748,0.0001232911,0.0002029693,0.00001524991,0.001056798,0.0003616531,0.0007877892],"category_scores_gemma":[0.0002364981,0.0001797948,0.0001154514,0.0002255439,0.000289644,0.0001377946,0.00041192,0.0003130323,0.00025142],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005109383,"about_ca_system_score_gemma":0.0001285827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004700935,"about_ca_topic_score_gemma":0.00006855505,"domain_scores_codex":[0.9978735,0.0004900133,0.0005691092,0.0003146998,0.00002495936,0.0007276922],"domain_scores_gemma":[0.9982838,0.0009289695,0.0002752045,0.0003964946,0.00008494111,0.00003055862],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001420487,0.0002959403,0.002257462,0.000009696371,0.0001329555,2.012081e-7,0.0005258608,0.000004115222,0.980398,0.0120479,0.000630156,0.002277249],"study_design_scores_gemma":[0.004029084,0.0005634106,0.003454235,0.00003268924,0.00002994398,0.00003926619,0.0004854884,0.00007966263,0.8695774,0.001162808,0.1202426,0.0003034018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9544882,0.02996062,0.004266487,0.002785759,0.002774745,0.003728158,0.0007825669,0.00006534118,0.001148146],"genre_scores_gemma":[0.9946551,0.0001082721,0.003363916,0.0007642381,0.00006294642,0.0002404155,0.0003516565,0.00003398572,0.0004195219],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1196124,"threshold_uncertainty_score":0.862574,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03993092026376419,"score_gpt":0.2869738930203625,"score_spread":0.2470429727565983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}