{"id":"W2028133066","doi":"10.1158/2159-8290.cd-13-0064","title":"Hit Parade for Adoptive Cell Transfer Therapy: The Best T Cells for Superior Clinical Responses","year":2013,"lang":"en","type":"letter","venue":"Cancer Discovery","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Adoptive cell transfer; Parade; Cell therapy; Cancer; Cancer therapy; Medicine; Cell; Computational biology; Computer science; Biology; T cell; Immunology; Internal medicine; Political science; Genetics; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001673976,0.0005113249,0.001158363,0.0004358083,0.0006280335,0.002037855,0.0005279208,0.006064226,0.00481157],"category_scores_gemma":[0.003917856,0.0002441918,0.0005199747,0.0003465411,0.001310166,0.001509545,0.0003991172,0.008333138,0.004401088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001461749,"about_ca_system_score_gemma":0.000677414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002114575,"about_ca_topic_score_gemma":0.0008158059,"domain_scores_codex":[0.9989587,0.0003202794,0.0001179497,0.0001444873,0.0003136145,0.0001449024],"domain_scores_gemma":[0.9987841,0.0007735442,0.00006022469,0.00007162712,0.0001746538,0.0001358531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002123722,0.0007338546,0.002779626,0.001065758,0.00008531778,0.01252429,0.0002709191,0.001511968,0.03326953,0.02634506,0.6418182,0.2774719],"study_design_scores_gemma":[0.002494575,0.002993021,0.003066328,0.0004047827,0.0001302475,0.01582408,0.0003932185,0.004493451,0.03574175,0.03923596,0.8950949,0.0001277065],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.03432459,0.05157603,0.008095619,0.8525653,0.02140886,0.0004511441,0.0005313208,0.0004272708,0.03061987],"genre_scores_gemma":[0.3101875,0.04862751,0.01512507,0.5055023,0.0578938,0.00101693,0.0007223572,0.0002852327,0.06063933],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.006064226,"threshold_uncertainty_score":0.01609623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.11753330179108,"score_gpt":0.3915685188405148,"score_spread":0.2740352170494348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}