{"id":"W2028137697","doi":"10.1016/j.autrev.2012.08.017","title":"Tregitope update: Mechanism of action parallels IVIg","year":2012,"lang":"en","type":"review","venue":"Autoimmunity Reviews","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Emory University","keywords":"Epitope; Antibody; FOXP3; Biology; Immune system; Immunology; In vitro; In silico; Antigen; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001701791,0.0009810553,0.005626146,0.0003570798,0.0003374957,0.00002011101,0.001443683,0.001838763,0.003620234],"category_scores_gemma":[0.0001173935,0.0007558134,0.001679183,0.0005267086,0.000449523,0.0002272452,0.0005422535,0.002082375,0.01461723],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000136995,"about_ca_system_score_gemma":0.0002487861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001915272,"about_ca_topic_score_gemma":0.00002031998,"domain_scores_codex":[0.992384,0.003790505,0.002305666,0.0005666746,0.00006668266,0.0008865022],"domain_scores_gemma":[0.9950768,0.0003112266,0.002386234,0.002082711,0.00009604472,0.00004702107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001241499,0.0003623994,4.093744e-7,0.009893045,0.0006213429,0.000001925556,0.00008309251,1.481257e-8,0.01050164,0.002588932,0.002642504,0.9732923],"study_design_scores_gemma":[0.0004016455,0.0001380568,0.000001321204,0.00533668,0.002538609,0.0003043816,0.00002278326,4.886788e-8,0.001052542,0.0001535447,0.9893873,0.0006630381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001914487,0.9929249,0.00008248755,0.00002871244,0.003067564,0.001831358,0.00007647234,0.0001381808,0.001831203],"genre_scores_gemma":[0.0001759163,0.9878665,0.0001133382,0.00006946961,0.00009286272,0.0003135739,0.00170733,0.00009726682,0.009563799],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9867448,"threshold_uncertainty_score":0.9994893,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1212194452861606,"score_gpt":0.3328900251991357,"score_spread":0.2116705799129751,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}