{"id":"W2028170369","doi":"10.1128/jvi.01828-12","title":"The N-Terminal Region of IFITM3 Modulates Its Antiviral Activity by Regulating IFITM3 Cellular Localization","year":2012,"lang":"en","type":"article","venue":"Journal of Virology","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":189,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"Biology; Endosome; Transmembrane protein; Amino acid; Virology; Virus; Cell biology; Influenza A virus; Viral replication; Mutant; Interferon; Cell; Genetics; Gene; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008056975,0.0001379744,0.0001190017,0.00005254704,0.000145437,0.0001471573,0.0001107372,0.000222716,0.001044789],"category_scores_gemma":[0.0001572144,0.00005262698,0.0001809477,0.00005267663,0.0001762048,0.0001048701,0.0001069456,0.00037193,0.0002713155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002593191,"about_ca_system_score_gemma":0.0001387172,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003738523,"about_ca_topic_score_gemma":0.0004359328,"domain_scores_codex":[0.9999342,0.00001240489,0.000006000376,0.00001044006,0.00001086619,0.00002614496],"domain_scores_gemma":[0.9999413,0.00001144718,0.00001692731,0.000005945575,0.000006674458,0.00001766882],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001892534,0.000008619926,0.0004749073,0.000007693953,0.00000236066,0.00004950307,0.000005553635,0.00003201738,0.9984812,0.00003588329,0.00002063268,0.0006922858],"study_design_scores_gemma":[0.00005259517,0.0002502427,0.02231087,0.000007029475,0.0000197799,0.0006873033,0.00004100857,0.001249708,0.973825,0.000101792,0.001449497,0.000005164943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998779,0.0002375428,0.0005122076,0.0000486933,0.000008327924,0.00000409779,0.00007211175,0.000008590192,0.0003292799],"genre_scores_gemma":[0.9991881,0.00006734974,0.0004059937,0.00002774221,0.000003032373,0.000005143386,0.0000832528,0.000003804536,0.0002156606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001044789,"threshold_uncertainty_score":0.003495157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01465584684825651,"score_gpt":0.2500372413435881,"score_spread":0.2353813944953316,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}