{"id":"W2028170570","doi":"10.1016/j.bbrc.2013.03.026","title":"Cysteine accessibility during As3+ metalation of the α- and β-domains of recombinant human MT1a","year":2013,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Trace Elements in Health","field":"Nursing","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Research Triangle Institute","keywords":"Chemistry; Metalation; Cysteine; Electrospray ionization; Metallothionein; Stereochemistry; Mass spectrometry; Biochemistry; Zinc; Enzyme; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002523727,0.0001953337,0.0001996798,0.00009558931,0.0002440435,0.00026103,0.000391467,0.0002198846,0.001697511],"category_scores_gemma":[0.0003511948,0.0001214984,0.0002069299,0.0002228022,0.0002115132,0.000190268,0.000116152,0.0003857928,0.0002574633],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004773817,"about_ca_system_score_gemma":0.0002281083,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004539561,"about_ca_topic_score_gemma":0.00418925,"domain_scores_codex":[0.9998367,0.00003355139,0.00001457174,0.00003728399,0.000030488,0.00004743648],"domain_scores_gemma":[0.9998168,0.0000475097,0.00004542041,0.00001883537,0.00004359053,0.00002782628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001302129,0.00004425583,0.0007944055,0.00005130716,0.00001967993,0.0001013339,0.0001451724,0.0001260784,0.9957202,0.0001742215,0.0001203225,0.001400884],"study_design_scores_gemma":[0.0000283017,0.0001415185,0.007625374,0.000008666734,0.00001908999,0.0002740097,0.0001036432,0.001104664,0.9883335,0.00008587459,0.002264201,0.00001121711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984872,0.000293105,0.000412238,0.0000562157,0.00001195731,0.000004136408,0.0001726264,0.00001278714,0.0005496379],"genre_scores_gemma":[0.9974796,0.0001415679,0.0003040419,0.00003289733,0.000003874573,0.000004197327,0.0005205752,0.00001601475,0.001497184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004539561,"threshold_uncertainty_score":0.009026229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0925694508073337,"score_gpt":0.4211855344297429,"score_spread":0.3286160836224092,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}