{"id":"W2028205665","doi":"10.1111/imr.12288","title":"The cooperation between the autophagy machinery and the inflammasome to implement an appropriate innate immune response: do they regulate each other?","year":2015,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Center for Advancing Translational Sciences; Science and Technology Development Fund; Cystic Fibrosis Foundation","keywords":"Autophagy; Biology; Inflammasome; Innate immune system; Endosome; Immune system; Cell biology; Lysosome; Phagosome; Mitophagy; Immunology; Intracellular; Inflammation; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.01471683,0.000876045,0.003302427,0.0001014902,0.000894157,0.0003295036,0.001323289,0.0004374602,0.00009306322],"category_scores_gemma":[0.001639905,0.0002812207,0.0008079211,0.0004941399,0.0005437661,0.000107314,0.0005656932,0.001349037,0.0002838849],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002046412,"about_ca_system_score_gemma":0.0003661992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004813764,"about_ca_topic_score_gemma":0.000003660149,"domain_scores_codex":[0.9880211,0.007900158,0.002150163,0.0007435913,0.0005185931,0.00066637],"domain_scores_gemma":[0.9946034,0.001466154,0.0009431596,0.002561524,0.0001893819,0.0002363748],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001129235,0.0000486609,0.000001733381,0.0004633933,0.0005061615,0.00001116141,0.0003334149,3.228155e-7,0.000032154,0.00268742,0.0001156624,0.9946707],"study_design_scores_gemma":[0.001432679,0.0005966292,0.0004576572,0.002542833,0.001219864,0.00006492762,0.00003083064,0.000004405835,0.000008071608,0.00169078,0.9915933,0.0003579934],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001855368,0.9859791,0.00002441768,0.002757071,0.0002273804,0.00874741,0.00005587013,0.0000988906,0.0002544973],"genre_scores_gemma":[0.0005770149,0.9946198,0.00007242266,0.0008299372,0.0004828085,0.002026431,0.0001380767,0.00008698594,0.001166466],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9943127,"threshold_uncertainty_score":0.999964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08427782229969806,"score_gpt":0.4033711018659915,"score_spread":0.3190932795662934,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}