{"id":"W2028209698","doi":"10.1139/v06-061","title":"Microwave-assisted regioselective synthesis of acyclic nucleosides through an alkylating reaction with 2-oxa-1,4-butanediol diacetate","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Microwave-Assisted Synthesis and Applications","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Regioselectivity; Chemistry; 1,4-Butanediol; Alkylation; Purine; Microwave irradiation; 2,3-Butanediol; Nucleobase; Catalysis; Organic chemistry; Microwave; Combinatorial chemistry; Enzyme; DNA; Fermentation; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001977285,0.0003026329,0.0005360815,0.00007906445,0.0002644508,0.00008227542,0.0004107644,0.0002451584,0.0002823443],"category_scores_gemma":[0.000166541,0.0002829085,0.0002101017,0.0002929753,0.0002584512,0.0003633692,0.00001065544,0.0004349181,0.000002837469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003744168,"about_ca_system_score_gemma":0.0009048154,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003832817,"about_ca_topic_score_gemma":0.005843196,"domain_scores_codex":[0.9981222,0.00003470369,0.0008133189,0.0003232309,0.000259687,0.0004468428],"domain_scores_gemma":[0.9972946,0.0002035293,0.001199737,0.0004727342,0.0004403536,0.0003890525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005111811,0.00007941605,0.001934221,0.0001347203,0.0001370972,0.00006272239,0.0002502019,0.00002580884,0.9913205,0.00004116387,0.0005484941,0.005414548],"study_design_scores_gemma":[0.0003460704,0.00002193271,0.002219399,0.0004844854,0.0001787307,0.0009391488,0.001374268,0.00001514223,0.9885712,0.0002522297,0.005282443,0.0003150037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9566861,0.0003830015,0.0001349511,0.0002220102,0.00002391659,0.00005499142,0.00007944031,0.00002061422,0.04239495],"genre_scores_gemma":[0.9965878,0.00004129663,0.002526375,0.00002552283,0.0003212926,0.00001276166,0.00002629645,0.00006400371,0.0003946103],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04200034,"threshold_uncertainty_score":0.9999623,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01147097274853597,"score_gpt":0.2099975497991781,"score_spread":0.1985265770506422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}