{"id":"W2028214577","doi":"10.1182/blood-2012-05-430389","title":"A new biologic prognostic model based on immunohistochemistry predicts survival in patients with diffuse large B-cell lymphoma","year":2012,"lang":"en","type":"article","venue":"Blood","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute","keywords":"International Prognostic Index; Medicine; Diffuse large B-cell lymphoma; Internal medicine; Oncology; Lymphoma; Rituximab; Tissue microarray; Immunohistochemistry; Vincristine; Survival analysis; Gene expression profiling; Pathology; Hematology; Cyclophosphamide; Chemotherapy; Biology; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001886486,0.0007081962,0.0007186192,0.0008453743,0.0002947573,0.0008120218,0.0006433511,0.0005183968,0.0008802887],"category_scores_gemma":[0.003941103,0.0002456167,0.0006255398,0.0002501958,0.0003579785,0.0003287698,0.0004452067,0.0006704211,0.000230588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008123632,"about_ca_system_score_gemma":0.0006323836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005234721,"about_ca_topic_score_gemma":0.004027316,"domain_scores_codex":[0.999597,0.0002017763,0.0000232465,0.00007239063,0.00004643205,0.00005913323],"domain_scores_gemma":[0.9979114,0.001489388,0.0002260796,0.00007161588,0.0001725234,0.0001291129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"observational","study_design_scores_codex":[0.001169643,0.0002835951,0.3026996,0.0000369574,0.0003591939,0.000357582,0.0001182378,0.6623827,0.001075092,0.0006882078,0.001988924,0.02884029],"study_design_scores_gemma":[0.00006082905,0.0001714659,0.01376068,0.00000856687,0.00008015479,0.0001729048,0.00002057352,0.9843614,0.0001574136,0.0009216337,0.0002722487,0.00001205381],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651738,0.0003751523,0.03137363,0.001079754,0.00006436338,0.00005878757,0.0006076372,0.0001784033,0.00108848],"genre_scores_gemma":[0.9956158,0.00006079846,0.003290329,0.00006615231,0.00002921117,0.00003966749,0.0005044217,0.00000861403,0.0003850583],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005234721,"threshold_uncertainty_score":0.01040852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00818017686283699,"score_gpt":0.2167461740695784,"score_spread":0.2085659972067414,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}