{"id":"W2028238072","doi":"10.1111/bcpt.12365","title":"The Adverse Effects of Sorafenib in Patients with Advanced Cancers","year":2014,"lang":"en","type":"review","venue":"Basic & Clinical Pharmacology & Toxicology","topic":"Thyroid Cancer Diagnosis and Treatment","field":"Medicine","cited_by":167,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"McGill University Health Centre; Capital Medical University; National Natural Science Foundation of China; McGill University","keywords":"Sorafenib; Medicine; Adverse effect; Oncology; Internal medicine; Thyroid cancer; Cancer; Angiogenesis; Tyrosine-kinase inhibitor; Pharmacology; Hepatocellular carcinoma","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006682304,0.0006035196,0.004179159,0.0001739824,0.00008699948,0.000002500115,0.0003947266,0.0007513106,0.0001256249],"category_scores_gemma":[0.0003436782,0.0003482291,0.0007604518,0.0003645809,0.0009389038,0.0000355021,0.0001454704,0.001246544,0.00006545561],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007622977,"about_ca_system_score_gemma":0.001551007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001965037,"about_ca_topic_score_gemma":0.0001283615,"domain_scores_codex":[0.9950222,0.001288759,0.001827666,0.0008839964,0.0002605399,0.0007168791],"domain_scores_gemma":[0.9909233,0.006782491,0.001256434,0.0005951545,0.0001475549,0.0002949959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001881825,0.00256526,0.01603894,0.005401658,0.002101094,0.0001613239,0.0000144265,0.000007443948,0.000001374469,0.00004611066,0.006405623,0.9653749],"study_design_scores_gemma":[0.01959956,0.008660344,0.03821333,0.003417931,0.006161297,0.000007188523,0.00000349448,0.000001875554,0.00001454895,0.00001026479,0.9235989,0.0003112074],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03571268,0.9541311,0.000002100526,0.0003848466,0.004204131,0.005230499,0.00002878853,0.00003934337,0.0002665738],"genre_scores_gemma":[0.01123027,0.9843174,0.00006856478,0.00180092,0.0004553359,0.001836718,0.00006496051,0.0000825832,0.0001432784],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9650637,"threshold_uncertainty_score":0.9998969,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02498928110811995,"score_gpt":0.4087074982565543,"score_spread":0.3837182171484344,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}